The siderophore transporter Sit1 is involved in the uptake of caspofungin by <i>Candida albicans</i>. [PDF]
Pedras A +8 more
europepmc +1 more source
Phenolic composition and multi‐target bioactivities of Globularia alypum extracts across seasons
Abstract Background This study investigates the influence of seasonal variation on the phytochemical profile and biofunctional activities of ethanolic leaf extracts from Globularia alypum. Leaves collected across four seasons were extracted with a hydroethanolic solvent (80:20, v/v) and analyzed by LC‐ESI‐MS/MS.
Mohammed Messaoudi +11 more
wiley +1 more source
Charge-Competition AIEgens Induce Mitochondrial Dysfunction for Selective Eradication of <i>Candida albicans</i> while Restoring Vaginal Microbiota. [PDF]
Zhang R +6 more
europepmc +1 more source
This study explores new antifungal strategies to combat non‐albicans Candida species. We tested clinically approved HDAC inhibitors—Vorinostat, Romidepsin, Tucidinostat—and the HDAC6/8‐selective MC1568, alone and with Fluconazole. The Fluconazole/MC1568 combination significantly enhanced antifungal activity and reduced biofilm formation.
Andrea Giammarino +10 more
wiley +1 more source
Diagnostic Potential of a Recombinant Candida albicans Hyr1 Protein. [PDF]
Bregón-Villahoz M +7 more
europepmc +1 more source
From Oral Candidiasis to Candidemia: A Review of Superficial to Invasive Progression
Recent and limited evidence indicates that oral candidiasis can disseminate Candida albicans throughout the body, leading to invasive candidiasis, such as candidemia, a life‐threatening infection. Considering antifungal resistance and global outbreaks of emergent non‐albicans Candida and related yeasts, murine models help understand dissemination ...
Julia Robledo Jerez +3 more
wiley +1 more source
Inducible gene deletion reveals essentiality of protein kinases and a septation initiation network in Candida albicans. [PDF]
Ramírez-Zavala B +6 more
europepmc +1 more source
Environmental and anthropogenic drivers of antibiotic resistance dissemination. The cycle reinforces how anthropogenic inputs, such as sewage, animal dung, hospital effluent, and agricultural runoff bring resistant bacteria and antibiotic residues into soil and water.
Punam Chowdhury +3 more
wiley +1 more source
AI-Powered Microscopic Diagnostic Techniques for <i>Candida albicans</i> Detection: A Systematic Review. [PDF]
Shoorgashti R, Jafari F, Lesan S.
europepmc +1 more source
Macrophage: Biological Functions, Diseases, and Therapeutic Targets
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun +4 more
wiley +1 more source

