Genetics of Candida albicans [PDF]
Candida albicans is among the most common fungal pathogens. Infections caused by C. albicans and other Candida species can be life threatening in individuals with impaired immune function. Genetic analysis of C. albicans pathogenesis is complicated by the diploid nature of the species and the absence of a known sexual cycle.
S, Scherer, P T, Magee
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ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan +12 more
wiley +1 more source
A candidíase, principal infecção fúngica do ser humano, é provocada por leveduras do gênero Candida, que fazem parte da microbiota endógena e exógena do corpo humano.
Luciana Furlaneto-Maia +4 more
doaj +1 more source
Extracellular aspartic protease SAP2 of Candida albicans yeast cleaves human kininogens and releases proinflammatory peptides, Met-Lys-bradykinin and des-Arg(9)-Met-Lys-bradykinin [PDF]
Bradykinin-related peptides, universal mediators of inflammation collectively referred to as the kinins, are often produced in excessive amounts during microbial infections.
Alexander Faussner +16 more
core +1 more source
Candida albicans Potassium Transporters
Potassium is basic for life. All living organisms require high amounts of intracellular potassium, which fulfils multiple functions. To reach efficient potassium homeostasis, eukaryotic cells have developed a complex and tightly regulated system of transporters present both in the plasma membrane and in the membranes of internal organelles that allow ...
Francisco J. Ruiz-Castilla +3 more
openaire +4 more sources
Macrophage Extracellular Traps in Immunity and Cancer
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Mechanisms underlying the exquisite sensitivity of Candida albicans to combinatorial cationic and oxidative stress that enhances the potent fungicidal activity of phagocytes [PDF]
Copyright © 2014 Kaloriti et al.Peer reviewedPublisher ...
Bohovych, Iryna +15 more
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A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park +11 more
wiley +1 more source
DAYA HAMBAT EKTRAK DAUN JARAK PAGAR (Jatropha curcas L) TERHADAP PERTUMBUHAN Candida albicans
Candida albicans merupakan jamur flora normal bersifat opportunistik didalam rongga mulut yang dapat menyebabkan terjadinya denture stomatitispada daerah rongga mulut.
Susi susi +3 more
doaj +1 more source
Cellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stress [PDF]
Acknowledgments We thank Alexander Johnson (yhb1D/D), Karl Kuchler (sodD/D mutants), Janet Quinn (hog1D/D, hog1/cap1D/D, trx1D/D) and Peter Staib (ssu1D/D) for providing mutant strains.
A Cederlund +51 more
core +3 more sources

