Results 41 to 50 of about 110,127 (261)

Absent in vitro interaction between chloroquine and antifungals against Aspergillus fumigatus [PDF]

open access: yes, 2017
This work was supported by Medical Mycology Section, Department of Medical Microbiology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Seyedmousavi, Seyedmojtaba   +3 more
core   +1 more source

Biotimer assay: A reliable and rapid method for the evaluation of central venous catheter microbial colonization [PDF]

open access: yes, 2017
Adherent bacteria and biofilm frequently colonize central venous catheters (CVCs). CVC colonization is correlated to infections and particularly to bloodstream ones.
Antimo Cutone   +8 more
core   +1 more source

Adhesion in Candida spp

open access: yesCellular Microbiology, 2002
Microbial adherence is one of the most important determinants of pathogenesis, yet very few adhesins have been identified from fungal pathogens. Four structurally related adhesins, Hwp1, Ala1p/Als5p, Als1p, from Candida albicans and Epa1p from Candida glabrata, are members of a class of proteins termed glycosylphosphatidylinositol-dependent cell wall ...
openaire   +2 more sources

Estudo de caso: Candida spp., Actinomyces spp. e diagnóstico diferencial

open access: yesRevista Brasileira de Análises Clínicas, 2022
Este estudo de caso referente a uma mulher de 37 anos com colo que apresenta características normais e com dispositivo intrauterino (DIU). Foi realizada uma colpocitologia através do método convencional e corada através da coloração Papanicolaou, cujas amostras foram reportadas como satisfatórias, apresentando zona de transformação. A nível microscópio
Mendonça, Paula   +3 more
openaire   +2 more sources

A Deep Representation Learning Method for Quantitative Immune Defense Function Evaluation and Its Clinical Applications

open access: yesAdvanced Science, EarlyView.
ImmuDef, a novel algorithm to quantitatively evaluate the anti‐infection immune defense function of an individual based on RNA‐seq data via a variational autoencoder (VAE) model. It is validated on 3200+ samples across four immune states with high accuracy. It can serve as a metric for disease severity and prognosis across pathogenic cohorts.
Zhen‐Lin Tan   +7 more
wiley   +1 more source

Addressing the silent threat: managing invasive Candida infections in hospitalized newborns

open access: yesFrontiers in Pediatrics
Invasive fungal infections (IFIs) remain an important problem for hospitalized newborn infants receiving intensive care, given their substantial morbidity and mortality.
Deshuang Zhang   +6 more
doaj   +1 more source

Novel 1,3-thiazolidin-4-one derivatives as promising anti-Candida agents endowed with anti-oxidant and chelating properties [PDF]

open access: yes, 2016
Pursuing our recent outcomes regarding the antifungal activity of N-substituted 1,3-thiazolidin-4-ones, we synthesized thirty-six new derivatives introducing aliphatic, cycloaliphatic and heteroaromatic moieties at N1-hydrazine connected with C2 position
Abdurrahman, Aktumsek   +10 more
core   +1 more source

CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis

open access: yesAdvanced Science, EarlyView.
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song   +14 more
wiley   +1 more source

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen   +12 more
wiley   +1 more source

Subgingival areas as potential reservoirs of different Candida spp in type 2 diabetes patients and healthy subjects.

open access: yesPLoS ONE, 2019
ObjectivesThe aim of this cross-sectional observational study was to compare the prevalence of different oral Candida spp. in patients with Type 2 Diabetes and chronic periodontitis in two oral sites: dorsal surface of the tongue and subgingival area. In
Sanja Matic Petrovic   +6 more
doaj   +1 more source

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