Results 191 to 200 of about 4,107,427 (327)

Multi-strategy embedded framework for neoantigen vaccine maturation. [PDF]

Sci Rep
Zhang G, Fu Y, Chan KC, Jin R, Yang Y, Fu L, Zhou R.   +6 more
europepmc   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

An international perspective on allocation rules for combined heart-lung transplantation. [PDF]

JHLT Open
Holm AM, Bello I, Sandiumenge A, Snell G, Gottlieb J.   +4 more
europepmc   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Eligibility for Extracorporeal Cardio-Pulmonary Resuscitation in Out-of-Hospital Cardiac Arrests in Sweden. [PDF]

Acta Anaesthesiol Scand
Ölander CH, Vikholm P, Olovsson I, Hellgren L.   +3 more
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Annual number of candidates for transcatheter aortic valve implantation per country: current estimates and future projections

European Heart Journal, 2018
Andras P Durko, Ruben L. J. Osnabrugge, N. Van Mieghem, M. Milojevic, D. Mylotte, V. Nkomo, A. Pieter Kappetein   +6 more
semanticscholar   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates.

Lancet. Infectious Diseases (Print), 2018
N. Mazur, Deborah Higgins, M. Nunes, J. Melero, Annefleur C Langedijk, Nicole M Horsley, U. Buchholz, P. Openshaw, J. McLellan, J. Englund, A. Mejías, R. Karron, E. Simões, I. Knezevic, O. Ramilo, P. Piedra, H. Chu, A. Falsey, H. Nair, L. Kragten-Tabatabaie, A. Greenough, E. Baraldi, N. Papadopoulos, J. Vekemans, F. Polack, Mair Powell, A. Satav, E. Walsh, R. Stein, B. Graham, L. Bont   +30 more
semanticscholar   +1 more source