Results 141 to 150 of about 29,388,619 (175)
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Identification and nucleotide sequence of the early region 1 from canine adenovirus types 1 and 2
Virus Research, 1989The genome of canine adenovirus type 1 (CAV-1) has been cloned and restriction maps compiled. These maps are compared with those of canine adenovirus type 2 (CAV-2). The left ends of both genomes were further characterised by DNA sequence analysis. Several features of the DNA sequence and predicted polypeptide sequence are similar to those of the human
Heather Cavanagh
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Australian Veterinary Journal, 2012 ObjectiveTo determine whether client‐owned dogs in Australia, last vaccinated withCanvac® vaccines containing canine parvovirus‐type 2 (CPV‐2), canine distemper virus (CDV), canine adenovirus type 2 (CAV‐2) ± canine parainfluenza virus (CPiV) at least 18 months ago, were seropositive or responded serologically to revaccination.MethodsA total of 235 ...
Mitchell, S. A. +4 more
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Cross-Protective Immunity to Canine Adenovirus Type 2 by Canine Adenovirus Type 1 Vaccination
American Journal of Veterinary Research, 1978SUMMARY Vaccination of dogs (n = 6) with a single dose of canine adenovirus type 1 (cav-1) vaccine in 1 experiment prevented clinical disease that was otherwise produced in nonvaccinated (control) dogs (n = 6) after they were given aerosol, challenge exposure with canine adenovirus type 2 (cav-2).
J B, Emery, J A, House, W R, Brown
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Genotypic characterization of type-2 variants of canine adenovirus
American Journal of Veterinary Research, 1986SUMMARY Two canine adenovirus (cav) isolates, apparently distinct from type-1 (Utrecht) and type-2 (Toronto A26/61) reference strains in their biochemical and/or immunologic properties, were submitted to DNA-restriction endonuclease analysis. Both isolates, designated IAF-81-2116 and IAF-75-95, appeared as genotypic variants of cav-2.
C, Hamelin, P, Jouvenne, R, Assaf
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Localization of Inflammation and Virions in Canine Adenovirus Type 2 Bronchiolitis
American Review of Respiratory Disease, 1990Abstract Beagle puppies develop bronchiolar inflammation and histamine hyperresponsiveness with canine adenovirus type 2 (CAV2) infections. We determined the distribution of bronchiolar lesions and correlated inflammation with virions and bronchoalveolar lavage fluid (BALF) cytology. Nineteen beagle puppies were inoculated with tissue
R, Grad +7 more
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Nucleotide sequence of E1 region of canine adenovirus type 2
Virology, 1989The nucleotide sequence of the leftmost EcoRI-C fragment (0 to 11.3%) of canine adenovirus type 2 (CAd2) which could transform rodent cells morphologically but required additional sequences from 10 to 32 map units (m.u.) for full expression of its oncogenic potential was determined. The EcoRI-C fragment contains 3609 nucleotide base pairs (bp) encoding
R, Shibata +3 more
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Journal of the American Veterinary Medical Association, 1980
SUMMARY A modified live strain of canine adenovirus type 2 (CAV-2) was developed and evaluated as a replacement for infectious canine hepatitis (canine adenovirus type 1; CAV-1) vaccines. In a genetic stability test, the vaccine strain remained nonpathogenic through five back passages in dogs and when given by the intranasal route.
E P, Bass, M A, Gill, W H, Beckenhauer
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SUMMARY A modified live strain of canine adenovirus type 2 (CAV-2) was developed and evaluated as a replacement for infectious canine hepatitis (canine adenovirus type 1; CAV-1) vaccines. In a genetic stability test, the vaccine strain remained nonpathogenic through five back passages in dogs and when given by the intranasal route.
E P, Bass, M A, Gill, W H, Beckenhauer
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In vitro functional genetic modification of canine adenovirus type 2 genome by CRISPR/Cas9
Laboratory Investigation, 2021Genetically modified oncolytic adenoviruses have been proposed as a vehicle for cancer therapy. However, several concerns, such as toxicity to normal cells and organs, lack of suitable cell surface receptors to allow viral entry to the desired cell type(s), and activation of both innate and adaptive immune systems in patients, restrict the successful ...
Abdul Mohin Sajib +7 more
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Canine adenovirus type 2 infection in four puppies with neurological signs
Veterinary Record, 2006Four nine‐ to 11‐week‐old puppies developed respiratory and neurological signs due to an infection with canine adenovirus type 2 ( CAV‐2 ); three of these were euthanased. They had moderate, diffuse pneumonia but there were no histological abnormalities in the central nervous system ...
V, Benetka +5 more
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Canine Adenovirus Type 2-Induced Immunity to Two Canine Adenoviruses in Pups with Maternal Antibody
American Journal of Veterinary Research, 1975SUMMARY Twenty-four Beagle pups with high levels of maternal antibody to canine adenovirus type 1 (CAV-1) and canine adenovirus type 2 (CAV-2) were oronasally inoculated with CAV-2 at 4 weeks of age. The CAV-2 was isolated from pharyngeal swabs on postinoculation days 2 through 6. In spite of the infection, maternal antibody continued to decrease for 4
M, Appel, L E, Carmichael, D S, Robson
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