Results 81 to 90 of about 18,801 (202)

Canine coronavirus infection in the dog following oronasal inoculation [PDF]

Research in Veterinary Science, 1991
The pathogenesis of canine coronavirus (CCV) infection in 10-week-old puppies was studied up to 14 days after oronasal inoculation. Mild diarrhoea was seen from three to 11 days after inoculation, approximately coincident with faecal virus shedding. Virus was initially isolated from the tonsils on day 3, and then from both small and large intestinal ...
Tennant, B.J., Gaskell, R.M., Kelly, D.F., Carter, S.D., Gaskell, C.J.   +4 more
openaire   +2 more sources

Interferon-lambda: A potent regulator of intestinal viral infections [PDF]

Interferon-lambda (IFN-λ) is a recently described cytokine found to be of critical importance in innate immune regulation of intestinal viruses. Endogenous IFN-λ has potent antiviral effects and has been shown to control multiple intestinal viruses and ...
Baldridge, Megan T, Lee, Sanghyun
core   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, Volume 15, Issue 8, 23 February 2026.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Canine coronavirus inactivation with physical and chemical agents

The Veterinary Journal, 2008
Canine coronavirus (CCoV) is responsible for mild or moderate enteritis in puppies. The virus is highly contagious and avoiding contact with infected dogs and their excretions is the only way to ensure disease prevention. Since no studies have yet focused on the sensitivity of CCoV to chemical biocides the present investigation examined the efficiency ...
openaire   +2 more sources

Follow-up monitoring in a cat with leishmaniosis and coinfections with Hepatozoon felis and ‘Candidatus Mycoplasma haemominutum’ [PDF]

Case summary A 6-year-old female neutered domestic shorthair cat from Cyprus was presented with multiple ulcerated skin nodules. Cytology and histopathology of the lesions revealed granulomatous dermatitis with intracytoplasmic organisms, consistent ...
Attipa, C, Baneth, G, Brooks-Brownlie, H, Martínez-Orellana, P, Nachum-Biala, Y, Neofytou, K, Solano-Gallego, L, Tasker, S, Yiapanis, C   +8 more
core   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, Volume 13, Issue 11, 23 February 2026.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

Pathogens associated with acute infectious canine tracheobronchitis in New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Masters in Veterinary Studies in Virology at Massey University, Turitea, Palmerston North, New Zealand [PDF]

Infectious canine tracheobronchitis (ICT) or canine infectious respiratory disease, commonly known as kennel cough, is an acute, highly contagious respiratory disease that affects the larynx, trachea, bronchi, and occasionally the parenchyma of the lower
Sowman, Harriett Rose
core  

Antimicrobial use Guidelines for Treatment of Respiratory Tract Disease in Dogs and Cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases [PDF]

Respiratory tract disease can be associated with primary or secondary bacterial infections in dogs and cats and is a common reason for use and potential misuse, improper use, and overuse of antimicrobials.
Allen, Angus, Bannasch, Barrs, Beatty, Bennett, Berryessa, Bexfield, Binns, Bongrand, Boothe, Bradley, Burns, Chalker, Chalker, Chan, Chandler, Confalonieri, Danish Small Animal Veterinary Association (SvHKS), Dear, Demetriou, Demko, Dossin, Drawz, Egberink, Ellis, Erles, German, Guardabassi, Hartmann, Helps, Henderson, Hollis, Hunter, Jameson, Johnson, Johnson, Johnson, Johnson, Johnson, Keil, Kogan, Kompare, Lee, Lees, Levy, Lionel, Litster, MacPhail, Maggs, Martino, McInnis, McKiernan, Meijvis, Melendez, Meyers, Mochizuki, Morley, Mulholland, Murphy, Owen, Papich, Parnham, Peeters, Pesavento, Priestnall, Priestnall, Proulx, Pui-Ying, Quimby, Quimby, Radhakrishnan, Renshaw, Rheinwald, Rheinwald, Rooney, Rozanski, Ruch-Galle, Ruch-Gallie, Ruch-Gallie, Schulz, Schwarz, Sparkes, Speakman, Speakman, Spindel, Stillion, Sturgess, Sykes, Tart, Trow, Tynan, Vanderkooi, Veir, Velineni, Viitanen, Waddell, Walker, Welsh, Westfall, Wong, Zhu   +101 more
core   +1 more source

Fertility and Early Embryonic Development Toxicity of hzVSF‐v13 in Sprague–Dawley Rats

Journal of Applied Toxicology, Volume 46, Issue 2, Page 560-568, February 2026.
ABSTRACT Humanized virus suppressing factor–variant 13 (hzVSF‐v13), a monoclonal IgG4 antibody, is a potential therapeutic candidate for COVID‐19. Although fertility and embryonic developmental toxicity studies are crucial for the safety evaluation of new drugs, the toxicological profile of hzVSF‐v13 remains unexplored.
Ji‐Seong Jeong, Sang‐Yun Kim, Jinsoo Lee, Seung‐Jin Lee, Onju Ham, Woojin Kim, Wan‐Jung Im, Sungman Park, Kyong‐Cheol Ko, Jong‐Choon Kim, Yong‐Bum Kim   +10 more
wiley   +1 more source

A Serological Survey of Canine Respiratory Coronavirus and Canine Influenza Virus in Korean Dogs

Journal of Veterinary Medical Science, 2010
The relationship between canine respiratory coronavirus (CRCoV) and canine influenza virus (CIV) seropositivity in dogs in Korea was examined. Sixty-two of the 483 samples (12.8%) were seropositive for CRCoV by indirect fluorescent antibody (IFA) analysis. Nineteen animals were seropositive for CIV by ELISA out of the 385 samples tested.
AN, Dong-Jun, JEOUNG, Hye-Young, JEONG, Wooseog, CHAE, Sungwon, SONG, Dae-Sub, OH, Jin-Sik, PARK, Bong-Kyun   +6 more
openaire   +3 more sources