Results 211 to 220 of about 127,380 (271)

Use of VetCompass Australia data to estimate body weight for antimicrobial stewardship in Australian dogs

open access: yesAustralian Veterinary Journal, EarlyView.
Evaluation of the appropriateness of antimicrobial use requires multiple data elements, including the indication for treatment, duration of therapy and dose of the drug used. To calculate the dose the volume of active ingredient and animal weight are required.
L Hardefeldt, K Li, K Bailey
wiley   +1 more source

Mandibular Arch Morphology in Normodivergent Patients With Impacted Maxillary Canines: A Case-Control Study. [PDF]

open access: yesInt J Dent
Lorusso M   +6 more
europepmc   +1 more source

Impact of climate on Australian, non‐Vector‐borne infectious animal diseases: A scoping review

open access: yesAustralian Veterinary Journal, EarlyView.
Changes to Australia's climate continue to be increasingly relevant for human, animal and planetary health, and have far‐reaching impacts on disease emergence and food security. There is a deficit of knowledge in Australia around how climatic conditions are affecting infectious animal diseases, beyond the more obvious spatial distribution changes of ...
G Terry, MP Ward
wiley   +1 more source

Peri‐oesophageal metastases of pulmonary adenocarcinoma presenting as dysphagia in a dog

open access: yesAustralian Veterinary Journal, EarlyView.
Primary pulmonary neoplasia represents approximately one percent of canine cancers. Although it is recognised that many of these cases may not display classic respiratory signs, dysphagia is not an expected presentation. This report describes a twelve‐year‐old Border Collie that presented with a history of progressive dysphagia and weight loss over ...
JM Beattie, A Teh
wiley   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

open access: yesBritish Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk   +2 more
wiley   +1 more source

Chemoproteomic discovery of a brain‐penetrant, covalent NLRP3 inhibitor that binds a novel allosteric pocket

open access: yesBritish Journal of Pharmacology, EarlyView.
NLRP3 is a promising inflammatory target, but existing inhibitors lack diversity and brain penetrance, and none are approved. Using chemoproteomics, we discovered a novel series that binds to Cys463 in a previously uncharacterized pocket. Compounds showed nanomolar potency, brain exposure, and in vivo suppression of IL‐1β, supporting neuroinflammatory ...
Donald C. Rogness   +21 more
wiley   +1 more source

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