Results 81 to 90 of about 1,218,921 (154)

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

Chemistry – A European Journal, Volume 32, Issue 34, 11 September 2026.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier, Duan Li, Leentje Persoons, Graciela Andrei, Robert Snoeck, Dominique Schols, Lieve Naesens, Xiao Jia   +7 more
wiley   +1 more source

Morbillivirus receptors and tropism: multiple pathways for infection

Frontiers in Microbiology, 2012
Morbilliviruses, which include measles virus (MeV), canine distemper virus, and rinderpest virus, are among the most important pathogens in their respective hosts and cause severe syndromes. Morbilliviruses are enveloped viruses with 2 envelope proteins,
Hiroki eSato, Misako eYoneda, Tomoyuki eHonda, Chieko eKai   +3 more
doaj   +1 more source

Multiplexed Metagenomic Deep Sequencing To Analyze the Composition of High-Priority Pathogen Reagents

mSystems, 2016
Laboratories studying high-priority pathogens need comprehensive methods to confirm microbial species and strains while also detecting contamination. Metagenomic deep sequencing (MDS) inventories nucleic acids present in laboratory stocks, providing an ...
Michael R. Wilson, Greg Fedewa, Mark D. Stenglein, Judith Olejnik, Linda J. Rennick, Sham Nambulli, Friederike Feldmann, W. Paul Duprex, John H. Connor, Elke Mühlberger, Joseph L. DeRisi   +10 more
doaj   +1 more source

Real‐Time and Non‐Invasive Detection of Respiratory Viral Infections Using an Intelligent Odor Monitoring System (IOMS)

Advanced Science, Volume 13, Issue 51, 14 September 2026.
An intelligent odor monitoring system integrates an IVC animal model, gas sensor array, real‐time resistance readout, and machine‐learning analysis to continuously monitor infection‐associated odor changes. The platform captures longitudinal sensor responses, distinguishes infected from healthy states, and supports early‐stage respiratory viral ...
Yajie Shen, Weifeng Yuan, Long Li, Yucheng Zheng, Kenan Liu, Hegeng Li, Hua‐Yao Li, Yongliang Zhao, Binzhou Ying, Lanpeng Guo, Wenjian Zhang, Shu‐Ming Kuo, Zirui Zhang, Yufan Deng, Bohan Yin, Zhaocheng Luo, Ke Xu, Huan Liu   +17 more
wiley   +1 more source

Applications of Mesenchymal Stromal Cells for Treatment of Diseases

MedComm, Volume 7, Issue 9, September 2026.
This schematic summarizes the major therapeutic mechanisms of MSCs across different disease systems and highlights factors associated with MSCs dysfunction, together with current strategies to enhance MSCs function and therapeutic efficacy. This summary diagram illustrates that MSCs exert therapeutic effects in various diseases through multiple ...
Dongmei Xue, Yongsheng Li, Lei Wu
wiley   +1 more source

A Novel CARMIL2 Immunodeficiency Identified in a Subset of Cavalier King Charles Spaniels with Pneumocystis and Bordetella Pneumonia

Journal of Fungi
Pet dogs are a valuable natural animal model for studying relationships between primary immunodeficiencies and susceptibility to Pneumocystis and other opportunistic respiratory pathogens.
Emily L. Coffey, Liang Ma, Ousmane H. Cissé, Joseph A. Kovacs, Katie M. Minor, Antti Sukura, Patrizia Danesi, Steven G. Friedenberg, Jonah N. Cullen, Christiane Weissenbacher-Lang, Julie C. Nadeau, Amber M. Graham, Martin N. Granick, Natalie K. Branson, Kyle C. Branson, Barbara Blasi, Casandra M. Jacobs, Eva Furrow   +17 more
doaj   +1 more source

Clinical Molecular Investigation of Encephalitozoon cuniculi in Pet Rabbits: Early Detection of Potential Risk for Animal and Human Infection

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This study assesses the presence, genotypes and clinical signs of E. cuniculi infection in pet rabbits in Slovenia. Molecular analysis reveals the presence of E. cuniculi DNA (Genotype I) in 14.98% rabbit urine samples, mostly in rabbits with signs of urinary tract disorders.
Maruša Škrbec, Brigita Slavec, Nina Kočar, Katarina Modrijan, Urška Kuhar, Marko Kolenc, Alenka Dovč, Olga Zorman Rojs, Jožko Račnik   +8 more
wiley   +1 more source

Feeding and Husbandry Practices in Pet Ferrets (Mustela putorius furo): A Cross‐Sectional International Study

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Clearer recommendations and improved caregiver education are urgently needed to support optimal ferret welfare. ABSTRACT Background The domestic ferret (Mustela putorius furo) is an increasingly popular non‐traditional companion animal; however, limited information is available on how caregivers manage feeding and husbandry practices.
Erdem Danyer, Giada Morelli, Lorenzo Serva, Elena Dal Corso, Diego Cattarossi, Marianne Diez, Rebecca Ricci   +6 more
wiley   +1 more source

The transmission dynamics of groups A and B human respiratory syncytial virus (hRSV) in England & Wales and Finland: seasonality and cross-protection [PDF]

, 2005
Human respiratory syncytial virus (hRSV) transmission dynamics are inherently cyclical, and the observed genetic diversity (between groups A and B) also appears to have a repeating pattern.
Waris, M, White, Lisa, Medley, GF, White, L. J., Medley, Graham, Waris, M., Cane, Patricia, Nokes, D. James, Nokes, DJ, White, LJ, Cane, PA   +10 more
core   +1 more source

Ecology of declining populations of gray foxes (Urocyon cinereoargenteus) in Indiana, USA Ecología de las poblaciones en declive de zorros grises (Urocyon cinereoargenteus) en Indiana, EE.UU.

Wildlife Monographs, Volume 226, Issue 1, September 2026.
We estimated seasonal space use, cover selection, and resource selection; evaluated gene flow and potential genetic barriers; and assessed cause‐specific survival rates and reproduction of radiomarked gray foxes in Indiana, USA. Our results provide evidence that gray foxes in Indiana are an edge species with relatively large home ranges, relatively low
Tim L. Hiller, Julia A. Nawrocki, Brandon M. Bernhardt, Lane K. Jeakle, Dawn M. Reding, Geriann Albers   +5 more
wiley   +1 more source