Two small placebo‐controlled trials evaluated the effects of cannabidiol (CBD) in patients with alcohol use disorder (AUD), with and without co‐occurring post‐traumatic stress disorder (PTSD). CBD was rapidly absorbed and generally well tolerated in dosages of up to 1200 mg/day. Both treatment groups showed large reductions in drinking.
Michael P. Bogenschutz +6 more
wiley +1 more source
Toxicity and health effects of delta-8, delta-9, and delta-10-tetrahydrocannabinol and unregulated cannabinoids in vaping products. [PDF]
Lin K +5 more
europepmc +1 more source
JWH-182: a safe and effective synthetic cannabinoid for chemotherapy-induced neuropathic pain in preclinical models [PDF]
Leontina-Elena Filipiuc +16 more
openalex +1 more source
Selective anti-cancer effects of cannabidiol and Δ9-tetrahydrocannabinol via PI3K/AKT/mTOR inhibition and PTEN restoration in ovarian cancer cells. [PDF]
Tong S +7 more
europepmc +1 more source
Use of oral neuromodulators in chronic pelvic painNumber 8 - 2025. [PDF]
Poli OB +16 more
europepmc +1 more source
Genotype–Specific Safety and Pharmacokinetics of Cannabidiol in Healthy Volunteers
ABSTRACT Cannabidiol (CBD) use has increased in America due to its widespread availability. Cannabidiol is metabolized by multiple polymorphic enzymes including CYP3A, CYP2C9, and CYP2C19. We sought to evaluate the genotype‐specific adverse events and pharmacokinetic profiles of cannabidiol, 7‐OH cannabidiol (an active metabolite), and 7‐COOH ...
Jumar Etkins +11 more
wiley +1 more source
From deficiency to toxicity: Magnesium increases cannabinoid and terpene production in cannabis plants. [PDF]
Morad D, Bernstein N.
europepmc +1 more source
ABSTRACT Issues From extracting insights from large‐scale, multimodal data to prevention and support, there is growing interest in the applications and implications of recent advances in Artificial Intelligence (AI) within the fields of addiction, substance use and mental health, which we refer to as ASUM.
Loïs Vanhée, Simone Scarpa
wiley +1 more source
Cannabis and cannabinoids in dermatology: a systematic review and meta-analysis of quantitative outcomes. [PDF]
Sermsaksasithorn P +4 more
europepmc +1 more source

