Results 231 to 240 of about 687,072 (327)

Advances and Strategies in Enhancing mRNA Cancer Vaccines

open access: yesAdvanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang   +4 more
wiley   +1 more source

A Programmable Nanovaccine Platform Based on M13 Bacteriophage for Personalized Cancer Vaccine and Therapy

open access: yesAdvanced Materials, EarlyView.
A reprogrammed (RP) phage‐based nanovaccine platform has been developed that allows single‐step assembly with precise control over adjuvanticity, antigen density, and nanoparticle size. By enhancing TLR9 activation and neoantigen display, this platform enables a potent personalized vaccine targeting tumor‐specific neoantigens. When combined with immune
Shengnan Huang   +10 more
wiley   +1 more source

Professional Quality of Life and Workplace Psychosocial Support Interventions among Nurses in the Philippines during the COVID-19 Pandemic. [PDF]

open access: yesActa Med Philipp
Castillejos JY   +6 more
europepmc   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Intrinsic and Extrinsic Determinants of Stability in Spiro‐OMeTAD‐Based Hole‐Transporting Layers in Perovskite Solar Cells: Mechanistic Insights and Strategic Perspectives

open access: yesAdvanced Materials, EarlyView.
This review provides a comprehensive and multidimensional examination of the intrinsic and extrinsic parameters that dictate the physicochemical stability of spiro‐OMeTAD‐based hole‐transporting layers. It further underscores recent breakthroughs in dopant molecular design, additive modulation, and strategies enabling post‐oxidation‐independence doping,
Yun Seop Shin   +5 more
wiley   +1 more source

A Lightweight, Flexible and Mechanically Robust Nonwoven Copper Metallized Nylon‐6 Fibers for Enhanced Charge Dissipation and Reduced Electrical Resistance for ESD Protection

open access: yesAdvanced Materials Interfaces, EarlyView.
A breathable and mechanically robust PA6 electrospun textile is modified via physical vapor deposition of a nanoscale copper layer, enabling efficient electrostatic charge dissipation. The resulting material exhibits a 99.6% decrease in triboelectric voltage and a 60% increase in tensile strength, offering a multifunctional solution for electrostatic ...
Piotr K. Szewczyk   +6 more
wiley   +1 more source

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