We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin +18 more
wiley +1 more source
Comparison of Attenuation Imaging in the Rectus Femoris and Biceps Brachii Muscles with Multiecho Dixon-Based Fat Quantification and Ultrasound Echo Intensity. [PDF]
Zoller S +5 more
europepmc +1 more source
Polymer‐based drug delivery systems can effectively overcome the limitations of free drugs in terms of solubility, stability, and plasma half‐life, yet their development has traditionally relied on time‐consuming trial‐and‐error approaches. This review highlights recent advances in applying molecular simulation to the design of polymer‐based drug ...
Ping Gao +4 more
wiley +1 more source
Detection of intracranial hemorrhage using ultralow-dose brain computed tomography with deep learning reconstruction versus conventional-dose computed tomography. [PDF]
Otgonbaatar C +8 more
europepmc +1 more source
Harnessing Advances in Bone Tissue Engineering for Design of Bone‐on‐Chip Systems
Bone‐on‐chip (BoC) systems demonstrate significant potential as next‐generation models to study human (patho)physiology and evaluate new therapies. However, progress toward functional, human‐like BoCs has been hindered by the structural and functional complexity of bone. This perspective discusses how insights from bone tissue engineering can guide BoC
Farhad Sanaei +6 more
wiley +1 more source
Surgical compared to percutaneous repair of aortic coarctation in the pediatric population: a protocol for a systematic review and meta-analysis update. [PDF]
Pérez-Ariza V +4 more
europepmc +1 more source
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen +9 more
wiley +1 more source
Deep learning-based automatic detection of pancreatic ductal adenocarcinoma ≤ 2 cm with high-resolution computed tomography: impact of the combination of tumor mass detection and indirect indicator evaluation. [PDF]
Ozawa M +11 more
europepmc +1 more source

