Results 61 to 70 of about 2,820,919 (248)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Dimensionality in canonical correlation of settlements characteristics and levels of infrastructure in rural Akwa Ibom State, Nigeria in 2014 [PDF]

open access: yesIranian Journal of Health, Safety and Environment, 2015
This study examines the relationship between rural settlements characteristics and access levels to infrastructural facilities in Akwa Ibom State. A total of 50 rural settlements were randomly selected and utilized for this study.
Uwem Ituen, Jacob Atser
doaj   +1 more source

Tensor canonical correlation analysis [PDF]

open access: yesStat, 2019
Canonical correlation analysis (CCA) is a multivariate analysis technique for estimating a linear relationship between two sets of measurements. Modern acquisition technologies, for example, those arising in neuroimaging and remote sensing, produce data in the form of multidimensional arrays or tensors.
Eun Jeong Min, Eric C. Chi, Hua Zhou
openaire   +4 more sources

PerseusDL/canonical-latinLit: None

open access: yes, 2021
XML Canonical resources for Latin ...
Marius Jøhndal   +19 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Presenting a model for measurement of the relationship between financial risks and financial ratios [PDF]

open access: yesمطالعات تجربی حسابداری مالی, 2019
All financial institutions and banks have risks in their operations that have not been able to eliminate them, but there is the possibility of managing these risks.
Bakhtiar Ostadi, Parvin Tadrisi Pajou
doaj   +1 more source

Integrative correlation: Properties and relation to canonical correlations

open access: yesJournal of Multivariate Analysis, 2014
The integrative correlation coefficient was developed to facilitate the validation of expression microarray results in public datasets, by identifying genes that are reproducibly measured across studies and even across microarray platforms. In the current study, we develop a number of interesting and important mathematical and statistical properties of
Leslie Cope   +2 more
openaire   +4 more sources

Sparse tensor canonical correlation analysis for micro-expression recognition

open access: yes, 2016
A micro-expression is considered a fast facial movement that indicates genuine emotions and thus provides a cue for deception detection. Due to its promising applications in various fields, psychologists and computer scientists, particularly those focus ...
Wang,Su-Jing   +4 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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