Advanced Healthcare Materials, EarlyView.This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
ICTD: Combination of Improved CNN-Transformer and Enhanced Deep Canonical Correlation Analysis for Eye-Movement Emotion Classification. [PDF]
Brain SciZhang C +5 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.TOC represents the synthesis of theory‐guided novel near‐infrared (NIR) light‐absorbing organic photosensitizers (OPS) enabling redox‐induced tumor phototherapy and single‐cell organelle tracking. ABSTRACT The design of organic photosensitizers that operate efficiently in the near‐infrared (NIR) region remains challenging due to the need to balance ...
Pragti +3 more
wiley +1 more source
Significance testing for canonical correlation analysis in high dimensions. [PDF]
Biometrika, 2022 McKeague IW, Zhang X.
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett +7 more
wiley +1 more source
Exploration of biomarkers of Alzheimer's disease based on orthogonal multi-task canonical correlation analysis. [PDF]
BMC Med ImagingYang T, Wan G, Zhou X.
europepmc +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Generalized probabilistic canonical correlation analysis for multi-modal data integration with full or partial observations. [PDF]
BMC BioinformaticsYang T, Li WV.
europepmc +1 more source
The association between quality of life and subjective wellbeing among older adults based on canonical correlation analysis. [PDF]
Front Public Health, 2023 Liu H +5 more
europepmc +1 more source
Resolving the Structural Duality of Graphene Grain Boundaries
Advanced Materials, EarlyView.Cantilever ncAFM resolves the atomic structure of grain boundaries in graphene, revealing coexisting stable and metastable types. Both contain pentagon/heptagon defects, but metastable GBs show irregular geometries. Modeling shows metastable GBs form under compression, exhibiting vertical corrugation, while stable GBs are flat.
Haojie Guo +11 more
wiley +1 more source