Results 161 to 170 of about 1,601,992 (295)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

A Matter of Font: Visual Word Form Area Responses to Brand Names Are More Sensitive to Font Than to Letter Case Changes. [PDF]

Neurobiol Lang (Camb)
Labusch M, Perea M, Davydova T, Pérez MB, Melle CC, Rodriguez EV, Zaragoza ER, Costumero V.   +7 more
europepmc   +1 more source

ANAM as the Canonical Name of X. Methodological Fixation of the Term and the Normative Language of Description

Description (EN) This publication provides a methodological fixation of the canonical term ANAM (X), introduced as a proper name for a universal integral fractal act of tense distinction. The article establishes normative rules of language that prevent the reduction of X to partial aspects such as “ground,” “principle,” “act,” “process,” or “mechanism.
openaire   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Correction: Canonical Ru(ii) tris-polypyridyl complexes as confocal-compatible stains for lignified secondary-wall domains in <i>Arabidopsis thaliana</i> stems. [PDF]

RSC Adv
Fuentes I, Fuentes JA, Carreño A, Cortés A, Sepúlveda-Orellana P, Saez-Aguayo S, Polanco R, Ancede-Gallardo E, Suárez AG, Otero MC, Leyva-Parra L, Martí AA, Moreno AA.   +12 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

SafeRx: A Canonical Pharmaceutical Knowledge Integration Framework for Multimodal Medication Safety. [PDF]

Bioengineering (Basel)
Radu AF, Radu A, Uivaraseanu B, Tit DM, Vesa CM, Bungau GS.   +5 more
europepmc   +1 more source