Results 111 to 120 of about 2,486,049 (309)
How canonical are Ashtekar's variables?
Physics Letters B, 1992 Abstract Attention is paid to the fact that in field theory a commutator of functional derivatives may differ from zero by surface integrals. Ashtekar's formalism is a primer which demonstrates that transformations looking locally canonical can lead to the appearance of surface terms in a symplectic form of field theory.
openaire +1 more source
Gauge Invariance and Canonical Variables
, 1999 We discuss some paradoxes arising due to the gauge-dependence of canonical variables in mechanics.
Khriplovich, I. B., Milstein, A. I.
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
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XSEDE Canonical Use Cases [PDF]
, 2013 This document is both a user-facing document (publically accessible) and an internal working document intended to define basic user needs and use cases within the overall activities of XSEDE.Submitted by Janet Brown (brown@psc.edu) on 2013-04-26T02:39 ...
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
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Interpretation and exegesis: An investigation into the canonical approach of B. S. Childs [PDF]
, 1999 We begin this study by delineating the canonical approach pioneered by B. S. Childs. Five critical perspectives on Childs' work follow raising important hermeneutical problems. M. G. Brett, C. J. Scalise and P. R.
Wilson, Norman Samuel
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
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PerseusDL/canonical-latinLit: 0.0.4734888628
, 2023 XML Canonical resources for Latin ...
Marius Jøhndal +19 more
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Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
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Three denials of time in the interpretation of canonical gravity [PDF]
, 2011 The analysis of the temporal structure of canonical general relativity and the connected interpretational questions with regard to the role of time within the theory both rest upon the need to respect the fundamentally dual role of the Hamiltonian ...
Thebault, Karim P Y, Karim P Y Thébault
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