Results 51 to 60 of about 3,709,591 (306)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Canonical correlation analysis for studying the relationship between egg production traits and body weight, egg weight and age at sexual maturity in layers

open access: yesCzech Journal of Animal Science, 2005
In this study, canonical correlation analysis was applied to layer data to estimate the relationships of egg production with age at sexual maturity, body weight and egg weight.
Y. Akbaş, Ç. Takma
doaj   +1 more source

Canonical analysis of non-relativistic string with non-relativistic world-sheet

open access: yesEuropean Physical Journal C: Particles and Fields, 2022
We perform canonical analysis of non-relativistic string theory with non-relativistic world-sheet gravity. We determine structure of constraints and symplectic structure of canonical variables.
Josef Klusoň
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Asymptotic model selection and identifiability of directed tree models with hidden variables [PDF]

open access: yes, 2010
The standard Bayesian Information Criterion (BIC) is derived under some regularity conditions which are not always satisfied by the graphical models with hidden variables.
Zwiernik, Piotr
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Canonical correlation analysis; An overview with application to learning methods

open access: yes, 2003
We present a general method using kernel Canonical Correlation Analysis to learn a semantic representation to web images and their associated text. The semantic space provides a common representation and enables a comparison between the text and images ...
Shawe-Taylor, John   +2 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

PerseusDL/canonical-greekLit 0.0.6

open access: yes, 2017
XML Canonical resources for Greek ...
Jeroen Hellingman   +21 more
core   +1 more source

Buğdayda Triticum aestivum Verim ve Vejetatif Bileşenler Arasındaki İlişkinin Araştırılması

open access: yesJournal of Agricultural Sciences, 2008
Bu çalışmanın amacı, ekmeklik buğday Gerek-79 cv’de ürün bileşenlerinin vejetatif bileşenler ile ne kadar ilişkili olduğunun araştırılmasıdır. Bu çalışmada biyolojik verim, dane verimi, 100 dane ağırlığı, hasat indeksi, fertile başakçık sayısı, başak ...
M. Muhip Özkan   +2 more
doaj  

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