Results 171 to 180 of about 342,635 (308)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Minimal N-hydroxyphthalimide-urethane bonds enable superior thermomechanical stability for covalent adaptable networks. [PDF]

Nat Commun
Yin Y, Yang S, Zhou Y, Yang Z, Qiao Z, Gao FL, Ma P, Bi QN, Wang S, Chen L, Tian W, Liu W, Xu J, Zhao N.   +13 more
europepmc   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

MOFs as New Catalytic Platform for Covalent Adaptable Networks: Catalysis Meets Reinforcement. [PDF]

Angew Chem Int Ed Engl
Renner S, Korotkov R, Mühlbacher I, Alfreider M, Kiener D, Liebhart J, Paris O, Slugovc C, Schlögl S, Rossegger E.   +9 more
europepmc   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Identification of tuna species used by the Portuguese canning industry through a DNA-based approach. [PDF]

Sci Rep
Silva MI, Viegas MB, Sousa F, Gordo LS, Paulo OS, Vieira AR.   +5 more
europepmc   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Multiorgan involvement with cardiac, renal and skeletal manifestations following inhalation of compressed air: A case report. [PDF]

Med Int (Lond)
Adrejiya P, Irshad S, Abubaker M, Neshat N, Maddika S, Sekar M.   +5 more
europepmc   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Effects of Isohexide Stereochemistry on Vinylogous Urethane Covalent Adaptable Networks. [PDF]

Macromolecules
Fanjul-Mosteirín N, Odelius K.
europepmc   +1 more source