Results 61 to 70 of about 80,327 (277)

Higher Complement C4 Gene Copy Number Constitutes a Shared Genetic Risk Factor for Giant Cell Arteritis and IgA Vasculitis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez   +295 more
wiley   +1 more source

Deucravacitinib in Active Psoriatic Arthritis: Efficacy and Safety Up to 52 Weeks From the Randomized, Double‐Blind, Phase 3 POETYK PsA‐2 Trial

open access: yesArthritis &Rheumatology, EarlyView.
Objective To assess the efficacy and safety of deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, in patients with psoriatic arthritis (PsA) who were naive to biologic disease‐modifying antirheumatic drugs or received tumor necrosis factor inhibitors. Methods In the 52‐week, double‐blind, placebo‐controlled, phase 3 Program for Evaluation
Philip J. Mease   +20 more
wiley   +1 more source

Efficiency and Perceptions in Public CSR: An Integrated Efficiency–Perception Analysis of Spanish Defence Delegations

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Public organisations often experience a discrepancy between improvements in technical efficiency and stakeholders' perceptions of integrity and performance. This study analyses the mechanisms that may underlie this efficiency–perception discrepancy in Spanish Defence Delegations during 2020–2023.
José Solana‐Ibáñez   +1 more
wiley   +1 more source

Pharmacokinetics and Safety of 1 mg Oral Minoxidil Tablets in Healthy Female Volunteers: A Phase I Randomized Crossover Clinical Trial

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Topical minoxidil is a first‐line treatment for female androgenetic alopecia (FAGA); however, its twice‐daily application, potential for scalp irritation and impact on hair texture can compromise adherence. Although low‐dose oral minoxidil has emerged as a promising alternative, standardized formulations with well‐characterized ...
Dolores Ochoa Mazarro   +2 more
wiley   +1 more source

Complete Remission of Superficial Basal Cell Carcinoma Using Automatic Patting System‐Assisted Topical 5‐Fluorouracil Therapy: Preliminary Clinical Evidence

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Topical 5‐fluorouracil (5‐FU) is a validated non‐invasive treatment for superficial basal cell carcinoma (sBCC), but its effectiveness may be limited by suboptimal skin penetration and local toxicity. Objectives To evaluate a galenic 5‐FU formulation delivered with Automatic Patting System (APS)‐assisted transdermal enhancement in ...
Francesco D'Oria   +3 more
wiley   +1 more source

Grothendieck and ℓ∞$\ell _\infty$‐Grothendieck Subspaces of ℓ∞$\ell _\infty$

open access: yesMathematische Nachrichten, EarlyView.
ABSTRACT Let c=2ℵ0$\mathfrak {c}=2^{\aleph _0}$. We prove that ℓ∞$\ell _\infty$ contains 2c$2^{\mathfrak {c}}$ pairwise non‐isomorphic non‐reflexive Grothendieck subspaces. They may all be chosen to contain the canonical copy of c0$c_0$ and to have an infinite‐dimensional reflexive quotient. This is optimal and answers Problem 24 of González and Kania [
Manuel González, Tomasz Kania
wiley   +1 more source

Comunicaciones libres del XIX Congreso. Santillana del Mar (Cantabria), 3 y 4 de junio de 2011 [PDF]

open access: yes, 2011
[ES] Resúmenes de las comunicaciones orales y póster presentados en el XIX Congreso regional de la Sociedad Otorrinolaringológica de Castilla y León, Cantabria y La Rioja celebrado los días 3 y 4 de junio de 2011 en Santillana del Mar (Cantabria).
Sociedad Otorrinolaringológica de Castilla y León, Cantabria y La Rioja
core  

The Circular Economy in European Union Supply Chains: A Literature Review

open access: yesSustainable Development, EarlyView.
ABSTRACT This research aims to analyze the implementation of the circular economy (CE) in European Union (EU) supply chains (SC), highlighting its potential to transform production systems and maximize resource efficiency while minimizing waste. Our study identifies the major trends and advancements in this field, focusing on the barriers that prevent ...
Luis Oswaldo Rodríguez‐Mañay   +2 more
wiley   +1 more source

Derecho y políticas ambientales en Cantabria (Segundo semestre 2016) [PDF]

open access: yes, 2014
Derecho y políticas ambientales en Cantabria (Segundo semestre ...
Gómez Puente, Marcos
core   +1 more source

Assessing the Performance of European Union Regions in the “People” and “Prosperity” Pillars of the SDGs

open access: yesSustainable Development, EarlyView.
ABSTRACT This paper addresses the gap in subnational assessments of Sustainable Development Goals (SDGs) by benchmarking the performance of European Union NUTS‐2 regions in the People and Prosperity pillars of the 2030 Agenda for Sustainable Development.
Pablo Arocena   +2 more
wiley   +1 more source

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