Results 151 to 160 of about 520,566 (286)

Simulation or cohort models? Continuous time simulation and discretized Markov models to estimate cost-effectiveness [PDF]

open access: yes
The choice of model design for decision analytic models in cost-effectiveness analysis has been the subject of discussion. The current work addresses this issue by noting that, when time is to be explicitly modelled, we need to represent phenomena ...
L Canto e Castro, Marta O Soares
core  

NAD replenishment restores mitochondrial function and thermogenesis in the brown adipose tissue of mice with obesity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A high‐fat diet (HFD) induces brown adipose tissue (BAT) whitening, mitochondrial dysfunction (damaged cristae, fragmentation), reduced NAD+ levels and impaired thermogenesis, leading to lower energy expenditure and metabolic inflexibility.
Renata R. Braga   +8 more
wiley   +1 more source

Stock Market Interactions and the Impact of Macroeconomic News – Evidence from High Frequency Data of European Futures Markets [PDF]

open access: yes
This study analyzes the short-term dynamic spillovers between the futures returns on the DAX, the DJ Eurostoxx 50 and the FTSE 100. It also examines whether economic news is one source of international stock return co-movements.
Bea Canto, Roman Kräussl
core  

Green Oil‐in‐Water Nanoemulsions for Delivery of Phytochemicals With Pesticidal Activity for Sustainable Food Production and Safety

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT Green oil‐in‐water (O/W) nanoemulsions incorporating essential oils (EOs) and food‐derived compounds are gaining prominence as biopesticidal platforms that address the growing demand for sustainable agriculture, food safety, and reduced chemical inputs.
Anna Paula Azevedo de Carvalho   +2 more
wiley   +1 more source

TEMPO MÁXIMO DE FONAÇÃO (TMF) EM CORALISTAS E NÃO CORALISTAS

open access: yesColloquium Vitae, 2018
O objetivo do estudo foi comparar o tempo máximo de fonação (TMF) de vozes coralistas e não coralistas. Participaram 40 pessoas, sendo 20 integrantes do coral do Curso de Licenciatura em Música da UNOESTE e 20 de participantes não coralistas.
Debora Godoy Galdino   +1 more
doaj  

Experimental evaluation of an intraoperative‐imaging based workflow for electron beam radiotherapy of pancreatic cancer using in situ dosimetry

open access: yesJournal of Applied Clinical Medical Physics, Volume 27, Issue 4, April 2026.
Abstract Purpose The aim of this study is to perform an experimental evaluation of an imaging‐based intraoperative electron beam radiotherapy (IOERT) and in vivo dose verification workflow for pancreatic cancer on a porcine cadaver. Materials and methods The Imaging Ring m (ImR) mobile cone‐beam computed tomography (CBCT) scanner (medPhoton GmbH ...
Charoula Iliaskou   +8 more
wiley   +1 more source

Extracellular Vesicles of Streptococcus anginosus Mediate Gastritis via Epithelial Barrier Disruption and Macrophage‐driven Inflammation

open access: yesAdvanced Science, Volume 13, Issue 19, 2 April 2026.
Streptococcus anginosus extracellular vesicles (SA‐EVs) accumulate in gastric tissue, disrupt epithelial tight junctions, and induce gastritis characterized by neutrophil infiltration and elevated cytokines (TNF‐α, IL‐6, IL‐17A). Proteomics identifies TMPC and FBP62 as key SA‐EVs virulence factors; their genetic deletion attenuates inflammation ...
Ying Gong   +12 more
wiley   +1 more source

Reply. [PDF]

open access: yesGastro Hep Adv
Canto MI   +4 more
europepmc   +1 more source

Stent Thrombosis: A Narrative Review From Pathophysiology to Therapy

open access: yesClinical Cardiology, Volume 49, Issue 4, April 2026.
Stent thrombosis remains a life‐threatening complication of PCI driven by complex interactions between stent design, procedural factors, thrombogenic milieu, and inflammation. This review integrates pathophysiological mechanisms with contemporary and emerging therapeutic strategies, highlighting optimized PCI, tailored antithrombotic therapy, and novel
Emanuele Cecchi   +8 more
wiley   +1 more source

Antiplasmodial Activity and Pharmacokinetic Profiling of Cryptolepine and 2,7‐Dibromocryptolepine With a View to Informing the Design of Novel Antimalarial Cryptolepine Analogues

open access: yesDrug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT The roots of the climbing shrub Cryptolepis sanguinolenta are traditionally used in West Africa for the treatment of malaria. The principal constituent, cryptolepine (1), has been shown to have antimalarial activity but there are concerns regarding its toxicity on account of its DNA‐intercalating property.
Elodie Chenu   +7 more
wiley   +1 more source

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