Results 171 to 180 of about 2,630 (258)

Rational Molecular Design to Improve Digital Polymer Readout in Aerolysin‐Based Nanopore Sequencing

open access: yesAngewandte Chemie, EarlyView.
Nanopore sensing holds significant yet underexplored potential for decoding synthetic digital polymers. In this study, we synthesized an extensive library of sequence‐defined poly(phosphodiester)s and evaluated their performance in aerolysin‐based sequencing. By systematically optimizing molecular parameters, we identified an ideal combination of coded
Zhaozheng Yang   +9 more
wiley   +2 more sources

High Diagnosis Rate for Nonimmune Hydrops Fetalis With Prenatal Clinical Genome: Expanded Results From the Hydrops‐Yielding Diagnostic Results of Prenatal Sequencing (HYDROPS) Study

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Nonimmune hydrops fetalis (NIHF) is characterized by abnormal fluid accumulation in ≥ 2 fetal compartments and may be genetic. The incremental diagnostic yield of prenatal exome sequencing (ES) for NIHF following a negative standard workup was previously explored on 22 cases.
Stephanie M. Rice   +10 more
wiley   +1 more source

Active‐Site Photothermal Energy Utilization in PET Depolymerization

open access: yesAngewandte Chemie, EarlyView.
Photothermal catalysis enables efficient PET depolymerization, yet the role of active‐site temperature remains unclear. A catalytic activity reversal between Pd–CNG and PdPOM–CNG is observed under thermal and photothermal conditions. Efficient nanoscale photothermal energy delivery raises active‐site temperature, compensates for lower intrinsic ...
Xin Li   +7 more
wiley   +2 more sources

Ac‐SDKP modulates apoptosis via HSP27 and the FAS/FASL and mitochondrial axes

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Schematic diagram of Ac‐SDKP regulating the FAS/FASL and mitochondrial apoptosis pathways via HSP27. Ac‐SDKP inhibits HSP27 expression, activates the FAS/FASL pathway and Caspase‐3 signaling, increases Caspase‐8 and Caspase‐3 expression, and induces cell apoptosis.
Wenxin Guo   +13 more
wiley   +1 more source

Engineering Atomically Precise Cu4I4 Nanoclusters With Integrated Adsorption and Hydrogenation Functions for Efficient Photocatalytic Nitrate‐to‐Ammonia Conversion

open access: yesAngewandte Chemie, EarlyView.
Efficient photocatalytic nitrate‐to‐ammonia conversion is achieved over an atomically precise Cu4I4 motif through dual‐site cooperation. Lewis‐acidic Cu centers promote nitrate adsorption and activation, while adjacent I sites facilitate active hydrogen generation for stepwise hydrogenation.
Wanting Zhang   +13 more
wiley   +2 more sources

Adaptation and validation for use in Brazil of the Confusion, Hubbub, and Order Scale (CHAOS). [PDF]

open access: yesPsicol Reflex Crit
de Espindola MI   +4 more
europepmc   +1 more source

Magnesium‐Retention Assisted Synthesis of High‐Performance Zintl Thermoelectrics

open access: yesAngewandte Chemie, EarlyView.
Mg volatilization and chemical instability during high‐temperature synthesis hinder the scalable fabrication of Mg‐based thermoelectrics. Here, a magnesium‐retention assisted synthesis (MRAS) strategy stabilizes Mg using a sacrificial Mg reservoir and an inert‐gas‐regulated melting environment.
Boxuan Hu   +9 more
wiley   +2 more sources

The forgotten airway: central airway pathology in the ICU. [PDF]

open access: yesFront Med (Lausanne)
Marchioni A   +9 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy