Results 21 to 30 of about 84,696 (154)

Selective glomerular hypofiltration is associated with glucometabolic disturbances in the general population. [PDF]

open access: yesJ Intern Med
Abstract Background Discordance between cystatin C‐ and creatinine‐based estimated glomerular filtration rate (eGFR) has been linked to adverse outcomes. A low eGFRcys/eGFRcr‐ratio, conceptualized as selective glomerular hypofiltration syndrome (SGHS), has been hypothesized to reflect early metabolic kidney vulnerability, although non‐glomerular ...
Nilsson C   +13 more
europepmc   +2 more sources

Mechanism and function of drosophila capa GPCR: a desiccation stress-responsive receptor with functional homology to human neuromedinU receptor [PDF]

open access: yes, 2012
The capa peptide receptor, capaR (CG14575), is a G-protein coupled receptor (GPCR) for the D. melanogaster capa neuropeptides, Drm-capa-1 and -2 (capa-1 and -2). To date, the capa peptide family constitutes the only known nitridergic peptides in insects,
Julian A. T. Dow   +37 more
core   +2 more sources

Insect capa neuropeptides impact desiccation and cold tolerance [PDF]

open access: yes, 2015
This work was funded by grants from the UK Biotechnology and Biological Sciences Research Council (BB/G020620 and BB/L002647/1) (to S.-A.D., J.A.T.D., and S.T.); US Department of Agriculture/Department of Defense Deployed War Fighters Protection Grant ...
Denlinger, David L.   +11 more
core   +1 more source

Downsizing the Histone H3–H4 Quaternary Structure Into Foldamer Mimetics Yields High‐Affinity and Cell‐Permeable Ligands of ASF1

open access: yesAngewandte Chemie, EarlyView.
We present a foldamer strategy to downsize the histone H3‐H4 quaternary structure into high‐affinity, medium‐sized binders (∼2 kDa) for the histone chaperone ASF1. Our peptide‐oligourea chimeras, designed through structure‐guided optimization and foldamer chemistry, recapitulate the natural H3‐H4 dimer binding mode while demonstrating plasma stability ...
Bo Li   +15 more
wiley   +2 more sources

CAPA 2023 Conference Invitation: CAPA 2023

open access: yes, 2023
Registration for CAPA 2023 Now Open! The CAPA Annual Conference is the only national conference designed for Canadian physician assistants by physician assistants. The conference attracts Canadian and international PAs looking for high-calibre continuing
CAPA-ACAM
core  

Successful Treatment of Primary Vaginal Diffuse Large B-Cell Lymphoma Using Chemotherapy

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2008
Objective: Non-Hodgkin's lymphomas (NHL) rarely affect the vagina. As a result, a standard treatment has not been defined. Case Report: A 34-year-old female virgin patient with a primary vaginal NHL stage IEA, diffuse large cell B lineage, showed an ...
Özgür Akbayir   +5 more
doaj   +1 more source

Reducing Aortic Barotrauma and Vascular Extracellular Matrix Degradation by Pacemaker‐Mediated QRS Widening

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background The extent of pressure‐related damage might be related to acceleration rate of the applied pressure (peak dP/dt) in the vascular system. In this study, we sought to determine whether dP/dt applied to the aortic wall (aortic dP/dt) and in turn ...
Murat Sezer   +11 more
doaj   +1 more source

ANAIS–112 three years data: a sensitive model independent negative test of the DAMA/LIBRA dark matter signal

open access: yesCommunications Physics
Weakly interacting massive particles (WIMPs) are well-motivated candidates for dark matter. One signature of galactic WIMPs is the annual modulation expected in a detector’s interaction rate, which arises from Earth’s revolution around the Sun.
Iván Coarasa   +14 more
doaj   +1 more source

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