Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
The intercultural development and validation of the Indigenous 'Escala de Bienestar Kankuamo' (Kankuamo Well-Being Scale): A capability approach. [PDF]
Van der Boor CF +7 more
europepmc +1 more source
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Realizing multispecies justice through a capability approach to promote nature-based solutions. [PDF]
Pineda-Pinto M +6 more
europepmc +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Scoring System for the Japanese Version of the ICECAP-A
Mitsuhiro Sado,1– 3 Kengo Nagashima,4 Akihiro Koreki2,3,5 1Keio University Health Center, Shinjuku-ku, Tokyo, Japan; 2Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan; 3Keio University Mindfulness & Stress Research Center ...
Sado M, Nagashima K, Koreki A
doaj
How can "small childcare" support "great happiness"? A study on inclusive childcare services for infants and toddlers aged 0-3 in Guangxi through the lens of the capability approach. [PDF]
Chen Z, Liu J, Li C, Kang Q, Tang Y.
europepmc +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Developing and agreeing a capability list in the British context: What can be learnt from social survey data on ‘rights’? [PDF]
The paper examines what can be learnt about the 'valuation' of freedoms and opportunities (or capabilities) using a general population social survey data source on values.
Polly Vizard
core

