Results 211 to 220 of about 638,237 (304)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Towards a capability approach to child growth: A theoretical framework. [PDF]

Matern Child Nutr, 2018
Haisma H, Yousefzadeh S, Boele Van Hensbroek P.   +2 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Higher capability maturity dynamics of UK construction organisations

This paper attempts to identify the dynamics of the CMM (Capability Maturity Model) higher capability maturity level characteristics within the UK construction context from a theoretical perspective.
Amaratunga, Dilanthi, Haigh, Richard, Keraminiyage, Kaushal   +2 more
core  

Thinking about Later Life: Insights from the Capability Approach. [PDF]

Ageing Int, 2018
Gopinath M.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Applications of the Capability Approach in the Health Field: A Literature Review. [PDF]

Soc Indic Res, 2017
Mitchell PM, Roberts TE, Barton PM, Coast J.   +3 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Capability Modeling: Initial Experiences

Enterprises operate in dynamically changing environments, consequently, information systems (IS) are a subject to continuous changes. The IS need to be adjusted to different customers, markets and run-time contexts affecting their design and delivery ...
Grabis, Jānis, Bravos, George, Koc, Hasan, Henkel, Martin, Gonzales, Tania, Stirna, Jānis, Jokste, Lauma   +6 more
core  

Understanding Settlement Pathways of African Immigrants in France Through a Capability Approach: Do Pre-migratory Characteristics Matter? [PDF]

Eur J Popul, 2018
Gosselin A, Desgrées du Loû A, Lelièvre E, Lert F, Dray-Spira R, Lydié N, Parcours Study Group.   +6 more
europepmc   +1 more source