Results 91 to 100 of about 332,273 (324)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
A Power Transformation for Non-Normal Processes Capability Estimation
IEEE AccessThe capability of a process is its ability to produce products that meet predefined requirements in industry and it is measured by capability indices. If data are not normally distributed, other techniques for capability estimation should be taken into ...
Silvija Lavrac, Goran Turk
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The K-trial. A 33-years study of the connections between manuring, soils and crops [PDF]
, 2005 In 1958 started a comparative fertilization trial, called the K-trial, within the frames of Scandinavian Research Circle for Biodynamic Agriculture. The trial ended in 1990.
Granstedt, Artur, Kjellenberg, Lars
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Early Results from VLT-SPHERE: Long-Slit Spectroscopy of 2MASS 0122-2439B, a Young Companion Near the Deuterium Burning Limit [PDF]
, 2015 We present 0.95-1.80 $\mu$m spectroscopy of the $\sim$12-27 $M_{\rm Jup}$ companion orbiting the faint ($R$$\sim$13.6), young ($\sim$120 Myr) M-dwarf 2MASS J01225093--2439505 ("2M0122--2439 B") at 1.5 arcsecond separation (50 AU).
Aller, Kimberly M. +10 more
core +4 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Utility of process capability indices in assessment of quality control processes at a clinical laboratory chain. [PDF]
J Clin Lab Anal, 2021 Dong P +7 more
europepmc +1 more source
Process capability indices when two sources of variability present, a tolerance interval approach [PDF]
, 2020 Éva Pusztai, Sándor Kemény
openalex +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
FEBS Open Bio, EarlyView.The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source