Results 41 to 50 of about 23,519 (258)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Impedance model for a high-temperature ceramic humidity sensor [PDF]

Journal of Sensors and Sensor Systems, 2019
We present an equivalent circuit model for a titanium dioxide-based humidity sensor which enables discrimination of three separate contributions to the sensor impedance.
H. Lensch, M. Bastuck, T. Baur, A. Schütze, T. Sauerwald   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

A Self-Compensating Non-Intrusive Ring-Type AC Voltage Sensor Based on Capacitive Coupling

Micromachines
In order to reduce the influence of coupling capacitance variations on cable voltage measurement, this paper proposes a self-compensating non-intrusive ring-type AC voltage sensor based on capacitive coupling.
Junpeng Wang, Jiacheng Li, Chunrong Peng, Zhengwei Wu, Dengfeng Ju, Qiang Zhang   +5 more
doaj   +1 more source

Dynamic laboratory measurement with dielectric sensor for forage mass flow determination

Research in Agricultural Engineering, 2007
A new parallel plate capacitance sensor was built consisting of two metal sheets. The sensor - a capacitor and the whole oscillating circuit was driven at 27 MHz frequency. Dynamic laboratory experiments were performed with grass from a natural meadow in
F. Kumhála, Z. Kvíz, J. Kmoch, V. Prošek   +3 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

A Capacitive Humidity Sensor Based on Multi-Wall Carbon Nanotubes (MWCNTs)

Sensors, 2009
A new type of capacitive humidity sensor is introduced in this paper. The sensor consists of two plate electrodes coated with MWCNT films and four pieces of isolating medium at the four corners of the sensor.
Zhen-Gang Zhao, Xiao-Wei Liu, Zhong-Xin Zhang, Wei-Ping Chen, Chun-Guang Suo   +4 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Pencil drawn interdigitated capacitive sensors on wood substrate

Advanced Sensor and Energy Materials
This research presents the fabrication and characterization of an interdigitated capacitive (IDC) sensor on a wooden substrate using pencil traces. The resistance of the pencil traces decreased from 100 kΩ to 5 kΩ as the pencil grade shifted from HB to ...
Abhay Singh Thakur, Vinit Srivastava, Rahul Vaish   +2 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source