Results 71 to 80 of about 28,744 (304)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Capacitive Soot Sensor

Procedia Engineering, 2015
AbstractA capacitive soot sensor was built up on basis of a known resistive device by covering the electrode area with a thin but dense alumina layer manufactured by the aerosol-deposition-method (ADM). Deposited soot cannot short-circuit the electrodes but leads to an increasing capacitance of the sensor.
Hagen, G., Rieß, G., Schubert, M., Feulner, M., Müller, A., Brüggemann, D., Moos, R.   +6 more
openaire   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Capacitive in-sensor tactile computing

Nature Communications
Abstract Real-time sensing and processing of tactile information are essential to enhance the capability of artificial electronic skins (e-skins), enabling unprecedented intelligent applications in tactile exploration and object manipulation. However, conventional tactile e-skin systems typically execute redundant data transfer and conversion
Yan Chen, Jie Cao, Jie Qiu, Dongzi Yang, Mengyang Liu, Mengru Zhang, Chenyang Li, Zhongyuan Wu, Jie Yu, Xumeng Zhang, Xianzhe Chen, Zhangcheng Huang, Enming Song, Ming Wang, Qi Liu, Ming Liu   +15 more
openaire   +2 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Capacitance Characteristics of Glass-Embedded Interdigitated Capacitors for Touch Sensing Applications

Sensors
This paper investigates the capacitance characteristics of a glass-embedded interdigitated capacitive sensor (IDCS) for touch-sensing applications. The study analyzes both baseline (no-touch) and touch-induced capacitance variations through a combination
Apichart Kaewcharoen, Kirote Arpanutud, Prayoot Akkaraekthalin, Phongsaphak Sittimart, Suramate Chalermwisutkul   +4 more
doaj   +1 more source

Fabrication and Characterization of CMOS-MEMS Magnetic Microsensors

Sensors, 2013
This study investigates the design and fabrication of magnetic microsensors using the commercial 0.35 μm complementary metal oxide semiconductor (CMOS) process.
Ming-Zhi Yang, Ching-Liang Dai, Chen-Hsuan Hsieh   +2 more
doaj   +1 more source

CAPACITIVE SENSOR AND METHOD TO PRODUCE SAID CAPACITIVE SENSOR.

, 2018
Capacitive sensor comprisng: a pad made of elastomeric insulating material in which at least one central part and at least one peripherical part are provided; an antenna made of electrical conductive material housed at least inside the internal part of the pad; and at least a restistor connected to teh antenna; at least the central part is provided ...
A. Bonarini, M. Romero, A. Brivio, M. Zambelli, M. Merigo, K. Rogacheva   +5 more
openaire   +2 more sources

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source