Results 31 to 40 of about 1,043,189 (284)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Cell-to-Cell Equalizer Based on Three-Resonant-State Switched-Capacitor Converters for Series-Connected Battery Strings

Energies, 2017
Due to the low cost, small size, and ease of control, the switched-capacitor (SC) battery equalizers are promising among active balancing methods. However, it is difficult to achieve the full cell equalization for the SC equalizers due to the inevitable ...
Yunlong Shang, Qi Zhang, Naxin Cui, Chenghui Zhang   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Active Capacitor Voltage Balancing Strategy for Stacked Flying Capacitor Half‐Bridge Five‐Level LLC Resonant Converter

IET Power Electronics
A multilevel DC–DC converter is a promising solution to save cost and promote the power density of DC solid‐state transformers. Among the multilevel DC–DC topologies, the stacked flying capacitor half‐bridge five‐level LLC resonant converter can ...
Daoxin Tong, Fan Zhang, Xu Yang, Jiajing Li, Yukun Niu, Wenjie Chen   +5 more
doaj   +1 more source

A predictive control with flying capacitor balancing of a multicell active power filter [PDF]

, 2008
Unlike traditional inverters, multicell inverters have the following advantages: lower switching frequency, high number of output levels, and less voltage constraints on the insulated-gate bipolar transistors.
Llor, Ana-Maria, Fadel, Maurice, Defaÿ, François   +2 more
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

A Modified Neutral-point Voltage Control Strategy for Three-level Inverters Based on Decomposition of Space Vector Diagram

CES Transactions on Electrical Machines and Systems, 2022
Capacitor voltage imbalance is a significant problem for three-level inverters. Due to the mid-point modulation of these inverter topologies, the neutral point potential moves up or down depending on the neutral point current direction creating ...
Dereje Woldegiorgis, H. Alan Mantooth
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

A selection principle of submodule switching state vectors for switching frequency reduction in voltage self‐balancing half‐bridge modular multilevel converters

IET Power Electronics
The problem of submodule switching frequency reduction in half‐bridge modular multilevel converters (HB‐MMCs) with capacitor voltage self‐balancing control is considered and explored in this paper.
Yiyuan Zhou, Liang Qin, Shiqi Yang, Qing Wang, Kaipei Liu   +4 more
doaj   +1 more source

Modified capacitor voltage balancing sorting algorithm for modular multilevel converter

The Journal of Engineering, 2019
The modular multilevel converter (MMC) with large-scale sub-modules has the advantage of simpler modulation, lower switching frequency, and lower harmonic component, thus would be very promising in voltage source converter (VSC)–high voltage direct ...
Jie Zhang, Jun Liu, Jiayu Liu, Wanliang Fang, Junxian Hou, Yifeng Dong   +5 more
doaj   +1 more source