Results 161 to 170 of about 8,341 (195)
Advanced Science, EarlyView.We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi +12 more
wiley +1 more source
Improvements to the ABSINTH Force Field for Proteins Based on Experimentally Derived Amino Acid Specific Backbone Conformational Statistics. [PDF]
J Chem Theory Comput, 2019 Choi JM, Pappu RV.
europepmc +1 more source
Structural Insights Into Man9 Recognition by the HIV Antibody 2G12 Revealed by Paramagnetic NMR
Advanced Science, EarlyView.The HIV gp120 glycoprotein displays Man9 oligomannose structures that are recognized by the neutralizing antibody 2G12. Detailed characterization of the binding epitope in solution is important for immunogen design but remains challenging, since the signals of the terminal mannoses from the three arms of Man9 (D1, D2, and D3) cannot be distinguished in
Adrián Silva‐Díaz +7 more
wiley +1 more source
The Necessity of Ambiguity in Self-Other Processing: A Psychosocial Perspective With Implications for Mental Health. [PDF]
Front Psychol, 2018 de Bézenac CE +2 more
europepmc +1 more source
Advanced Science, EarlyView.ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley +1 more source
A Survey on Security and Privacy in Emerging Sensor Networks: From Viewpoint of Close-Loop. [PDF]
Sensors (Basel), 2016 Zhang L, Zhang H.
europepmc +1 more source
Advanced Science, EarlyView.We report the development of biotinylated PEGylated bilirubin‐coated perfluoropentane (bt‐PEG‐BR@PFP) nanobubbles, a novel class of ROS‐activatable and dual‐modality contrast agents that amplify both ultrasound (US) and magnetic resonance imaging (MRI) signals in response to elevated ROS.
Wonsik Jung +6 more
wiley +1 more source
Insights into immune structure, recognition, and signaling. [PDF]
Immunol Rev, 2012 Garcia KC.
europepmc +1 more source
Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology
Advanced Science, EarlyView.Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu +4 more
wiley +1 more source