Results 191 to 200 of about 6,277,399 (213)

Ribonucleotides Amplify Mitochondrial DNA‐Driven cGAS–STING Activation via FdUMP‐ribonucleotide Hybrid Particles to Potentiate Chemoimmunotherapy

Advanced Science, EarlyView.
This work develops a metabolic sharing strategy that employs cytidine monophosphate (CMP) to competitively reprogram floxuridine (FUDR) pyrimidine metabolism in colorectal tumor cells. Elevated intracellular FdUMP induces nucleotide imbalance, drives mitochondrial DNA release and cGAS‐STING innate immune cascade activation, and potentiates robust ...
Chao Wang, Chenxuan Zhao, Yesong Yao, Zhiwen Zou, Anxin Shi, Zhuo Feng, Mingkang Yang, Yue Yu, Yang Liu, Xuehui Rui, Jinhui Wu   +10 more
wiley   +1 more source

Tumor Mechanical Remodeling via Bidirectional Calcium Redistribution Enables Deep Photothermal‐Immunotherapy

Advanced Science, EarlyView.
A bidirectional calcium‑redistributing nanomodulator rewires intra‑extracellular calcium homeostasis to remodel tumor mechanical microenvironments. It softens tumor stroma to facilitate deep tissue penetration while stiffening tumor cells, evoking amplified immunogenic cell death and robust CTL infiltration, which achieves potent deep photothermal ...
Hongjuan Zhao, Jinpei Sun, Chenxi Zhao, Yuting Cang, Keyu Zong, Yuxin Guo, Yajing Wang, Di Meng, Qingling Song, Lei Wang   +9 more
wiley   +1 more source

FTSJ3‐Mediated 2′‐O‐Methylation of HSPA5 mRNA Stabilizes BOP1 via SUMOylation to Drive DRP1‐Dependent Mitochondrial Fission and Fatty Acid Oxidation in Lung Squamous Cell Carcinoma

Advanced Science, EarlyView.
The RNA methyltransferase FTSJ3 drives lung squamous cell carcinoma progression by catalyzing 2′‐O‐methylation of HSPA5 mRNA, which stabilizes BOP1 through SUMOylation and activates DRP1/SREBP1‐mediated mitochondrial fission and fatty acid oxidation. Targeting this axis with liposomal siRNA potently suppresses tumor growth and metastasis ABSTRACT Lung ...
Qin Hu, Jiaheng Lin, Yifei Zhu, Ying Liu, Guoren Zhou   +4 more
wiley   +1 more source

Ordnungen und Beschlüsse amtliche Bekanntmachungen der Handwerkskammer Frankfurt (Oder) - Region Ostbrandenburg

, 2008
Handwerkskammer Frankfurt (Oder) - Region Ostbrandenburg
core  

Results on the Rate-Equivocation Region of the Degraded Signal-Dependent Noise Wiretap Channel

IEEE Communications Letters, 2020
This letter studies the rate-equivocation region of a degraded signal-dependent noise wiretap channel (SDGN-WC), where the noise is Gaussian. This signal-dependent noise occurs in optical wireless communication (OWC) settings based on intensity ...
Zouheir Rezki, Morteza Soltani
exaly   +2 more sources

Improved rate-equivocation regions for secure cooperative communication

, 2011
A simple four node network in which cooperation improves the information-theoretic secrecy is studied. The channel consists of two senders, a receiver, and an eavesdropper.
Vincent Poor, Ninoslav Marina
exaly   +2 more sources

A new achievable rate-equivocation region for the relay-eavesdropper channel

, 2010
In this paper, we propose an information-theoretic scheme which achieves a new rate-equivocation region for the four-terminal relay-eavesdropper channel.
Amir Sonee, Somayeh Salimi
exaly   +2 more sources

New Results on The Rate-Equivocation Region of The Optical Wiretap Channel with Input-Dependent Gaussian Noise with an Average-Intensity Constraint

, 2020
This paper studies the degraded optical wiretap channel with an input-dependent Gaussian noise when the channel input is only constrained by nonnegativity and average-intensity constraints. We consider the rate-equivocation region of this wiretap channel
Zouheir Rezki, Morteza Soltani
exaly   +2 more sources

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Capacity-Equivocation Region of the Gaussian MIMO Wiretap Channel

IEEE Transactions on Information Theory, 2012
Sennur Ulukus, Ersen Ekrem
exaly  

Capacity-equivocation region of a special case of wiretap channel with noiseless feedback

Journal of Communications and Networks, 2015
Zheng Ma, A J Han Vinck
exaly