Results 191 to 200 of about 4,646,161 (317)

A multidimensional biomarker model of vitality and its associations with intrinsic capacity and frailty. [PDF]

J Nutr Health Aging
Chew J, Chia JQ, Lim JP, Yeo A, Tan CN, Chan SP, Lim CL, Lim WS.   +7 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Recent progress on iron-based hexacyanoferrates for advanced potassium-ion batteries. [PDF]

Chem Sci
Zhou M, Zhang M, Zhang Q, Ma X, Fang H, Dong H, Chen X, Sun J, Li L, Zhou X.   +9 more
europepmc   +1 more source

Seasonally adjusted capacity and traffic.

Description based on: Dec. 1979; title from cover.Microfiche.Microfiche.Mode of access: Internet.Issued by Civil Aeronautics Board, Economic Evaluation Division, 1977- ; by the Board's Financial Analysis and Cost Division, -Dec.
United States. Civil Aeronautics Board. Financial Analysis and Cost Division., United States. Civil Aeronautics Board. Office of Economic Analysis., United States. Civil Aeronautics Board. Economic Evaluation Division.   +2 more
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Pricing decisions of converted and expanded enterprises for medical supplies under major public health emergencies. [PDF]

Front Public Health
Du L, Fan M, Lin Y.
europepmc   +1 more source

Capacity Analysis and Fisheries Policy: Theory versus Practice

Capacity analysis, capacity policy, data envelopment analysis, bioeconomic models, Resource /Energy Economics and Policy, Q22, Q28, D24,
Pascoe, Sean
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Optimising the prostate cancer diagnostic pathway in a tertiary hospital in Karachi: a two-cycle quality improvement project. [PDF]

BMJ Open Qual
Samad S, Samad H.
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source