Results 61 to 70 of about 5,544,499 (307)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Dolutegravir use over 48 weeks is not associated with worsening insulin resistance and pancreatic beta cell function in a cohort of HIV-infected Ugandan adults

open access: yesAIDS Research and Therapy, 2023
Background The Uganda Ministry of Health issued restrictive guidelines on the use of dolutegravir (DTG) in persons stratified to have a heightened risk of diabetes mellitus.
Frank Mulindwa   +8 more
doaj   +1 more source

Pulford Justin, Crossman Susie, Begg Sara, Amegee Quach Jessica, Abomo Pierre, El Hajj Taghreed and Bates Imelda, 2020, "Strengthening research management and support services in sub-Saharan African universities and research institutions - anonymous data extraction"

open access: yes
Intermediary data extracted from 28 research management system capacity assessment reports completed in 25 universities/research institutions from across 15 sub Saharan-African countries between 2014 and ...
Centre for Capacity Research
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Dynamic Characteristics of Suspended Load and Bed Load Transport in Meltwater Runoff of Qiyi Glacier

open access: yesShuitu Baochi Xuebao
[Objective] The transportation of sediment via glacial meltwater can not only reflect the glacial erosion and landform evolution, but also is one of the important sediment sources for the downstream river.
ZHAO Yi   +5 more
doaj   +1 more source

Monitoring and evaluation for capacity strengthening

open access: yes, 2023
Capacity challenges thwart economic growth and development. Efforts to strengthen capacity can benefit from past lessons and documented best practices. This note uses IFPRI’s capacity-strengthening activities as an example to provide an overview of best ...
Babu, Suresh Chandra   +1 more
core   +1 more source

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