Results 61 to 70 of about 4,646,161 (317)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Interview guide used across 5 test facilities in 3 African countries to explore enablers, barriers and effects of a research capacity strengthening programme, targeting development of a Quality Management System compliant with Good Laboratory Practice ...
Capacity Research, Centre for
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Informatics, 2020 Increasing complexity of societal questions requires participatory processes that engage with capable participants. We adopted Horellis’ stance on participation as not an isolated event but a constant communication between different groups that can
Teodora Iulia Constantinescu +1 more
doaj +1 more source
Intermediary data extracted from 28 research management system capacity assessment reports completed in 25 universities/research institutions from across 15 sub Saharan-African countries between 2014 and ...
Centre for Capacity Research
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Journal of the Royal Anthropological Institute, 2003 This article is about space and social relationships. More precisely, it is about the space of and in social relationships. It is also about the efficacy of social relationships in segregating their own contexts of meaning and value. The article also addresses the question of how agency comes about.
openaire +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Cybersecurity Capacity Review – Federative Republic of Brazil
, 2020 Excerpt from the executive summary - The Global Cyber Security Capacity Centre (GCSCC or ‘the Centre’) undertook a review of the maturity of cybersecurity capacity in Brazil at the invitation of, and in collaboration with, the Secretariat of the Inter ...
Global Cyber Security Capacity Centre
core +1 more source