Results 241 to 250 of about 2,268,216 (315)

Two years of genomic surveillance capacity development in Guinea: an operational roadmap for local implementation in low-income countries and tracking of SARS-CoV-2 circulation dynamics

Magassouba M, Gustani-Buss E, Ifono K, Nelson EV, Camara J, Giuditta A, Renevey A, Hinzmann J, Hinrichs M, Ryter S, Emua E, Millimono SL, Kolie E, Condé M, Sylla B, Ibrahim N, Mely S, Soubrier H, de Bellocq JG, Escudero-Pérez B, Cuypers LN, Moissonnier E, De Caluwé L, Müller J, Thielebein A, Tomazatos A, Jacobsen C, Pahlmann M, Becker-Ziaja B, Erameh C, Okogbenin S, Koundouno FR, Sidibé Y, Keïta K, Keita MB, Loi G, Kipela MFJM, Ki-Zerbo GA, Dia S, Lemey P, Günther S, Camara, Soropogui B, Kafetzopoulou LE, Boumbaly S, Duraffour S.   +45 more
europepmc   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Capacity development package

For selected CSs, and in close consultation with stakeholders, the knowledge gained and tools developed through the other WPs, strategies/MPs will be developed to address the sustainability of fisheries and aquaculture activities considering climate impacts and make these systems more resilient to possible climate-related ...
openaire   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Publication Watch

Space and Culture, India, 2015
Dr Rituparna Bhattacharyya
doaj  

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Developing environmental capacity

, 2006
openaire   +1 more source