Results 21 to 30 of about 64,427 (216)

A 35-gene signature discriminates between rapidly- and slowly-progressing glioblastoma multiforme and predicts survival in known subtypes of the cancer

BMC Cancer, 2018
Background Gene expression can be employed for the discovery of prognostic gene or multigene signatures cancer. In this study, we assessed the prognostic value of a 35-gene expression signature selected by pathway and machine learning based methods in ...
Azeez A. Fatai, Junaid Gamieldien
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Challenges and opportunities for greater public-private partnership for the implementation of the WHO operational framework for building climate resilient health systems to improve malaria control and elimination in Sub-Saharan Africa: a rapid review

Frontiers in Health Services
The relationship between climate change and malaria is complex, with both predictable and unpredictable aspects. The impacts of climate change may promote mosquito breeding, increase parasite development rates and extend the geographical range of malaria
Sheila Lumumba, Samuel Kamau, Isaac Ntwiga, Josphat Martin Muchangi, Jackline Kiarie, Sarah Kosgei, Moses Mwamburi, George Kimathi   +7 more
doaj   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

HIV viral load suppression and associated factors among PLHIV with non-communicable diseases in Uganda’s Teso Region: a cross-sectional retrospective study

AIDS Research and Therapy
Background As Uganda scales up integrated chronic care, understanding viral load suppression (VLS) among people living with HIV (PLHIV) with non-communicable diseases (NCDs) is critical for optimizing service delivery.
Bonniface Oryokot, Saadick Mugerwa Ssentongo, Abraham Ignatius Oluka, Timothy Otaala, Halima Sairo, Abel Muniina, Denis Jacob Olweny, Baker Bakashaba, Antonio Rodriguez Andres   +8 more
doaj   +1 more source

Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge, Maite E. Houwing, Rowena L. Grohssteiner, Ferdows Atiq, Sonja A. M. C. Teuben, Mirjam P. Fransen, Marjon H. Cnossen   +6 more
wiley   +1 more source

Maternal and infant predictors of early mother-to-child transmission among HIV-exposed infants in the Karamoja region, Northeastern Uganda 2020–2023, a retrospective cross-sectional study

BMC Infectious Diseases
Background Despite Uganda making significant progress in reducing mother-to-child transmission (eMTCT), from 20% in 2000 to 2.8% in 2021, regional differences in MTCT rates exist.
Saadick Mugerwa Ssentongo, Susan Alwedo, Bonniface Oryokot, Ronald Opito, Lameck Bukenya, Simon Peter Ijala, Robin Chepukurui, Peter Sekiranda, Timothy Otaala, Rogers Kyagulanyi, Yunus Miya, Baker Bakashaba   +11 more
doaj   +1 more source

Return to care of children and adolescents living with HIV who missed their clinic visits or were lost to follow-up: a continuous quality improvement study in Uganda

BMJ Open Quality
Background While the UNAIDS 95-95-95 targets have been met among adults, those for children and adolescents remain suboptimal. This study aimed to improve the return-to-care rates among children and adolescents living with HIV (CALHIV) who missed clinic ...
Jonathan Izudi, Kenneth Mugisha, Ssentongo Mugerwa Saadick, Boniface Oryokot, Ronald Opito, Baker Bakashaba, Abel Munina, kokas Opolot, Daniel Ogwal, Julius Ssendiwala   +9 more
doaj   +1 more source

Gender Empowerment in Agriculture Interventions: What Are We Still Missing? Evidence From a Randomized-Controlled Trial Among Coffee Producers in Honduras

Frontiers in Sustainable Food Systems, 2021
Latin-American coffee production has largely relegated women to specific family labor tasks, such as berry picking or cooking. But recent years have seen an increasing number of interventions to empower women in the agricultural sector, including coffee.
Karla Rubio-Jovel
doaj   +1 more source

Capacity Building in Development Projects

Procedia - Social and Behavioral Sciences, 2012
Development projects of different types mainly aim to alleviate poverty and ameliorate the livelihoods of local people. One of the strategies commonly used is to focus on organizations and build from their existing capacities in order to improve their living standards or try to build new organizations to work in a common project.
Sastre Merino, Susana, Ríos Carmenado, Ignacio de los   +1 more
openaire   +2 more sources