Results 61 to 70 of about 2,268,216 (315)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
South-South Capacity Development : The Way to Grow?
, 2007 A growing body of evidence suggests that learning and cooperation among developing nations is increasing n both frequency and complexity and expanding from just economic cooperation to include a variety of
Tejasvi, Ajay
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Breve 13: Strengthening Governments Capacity to Discern Value the Need to Address Technological Pressure on Health Expenditure [PDF]
, 2016 This Breve presents the story of how, in recent years, the Colombian health system has struggled with technological pressure. The impact of technological pressure on the health sector during the last few years could be summarized by either of two phrases:
Inter-American Development Bank
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
BMC Infectious DiseasesBackground Malaria is a significant public health problem, particularly among children aged 6–59 months who bear the greatest burden of the disease. Malaria transmission is high and more pronounced in poor tropical and subtropical areas of the world ...
Wisdom Kwami Takramah +2 more
doaj +1 more source
AIMT Journal of Management, 2019 The Vision of 'Make in India' is to achieve self-reliance through building indigenous capabilities for manufacturing and maintenance of defence equipment in a cost effective manner. Industries are partners of the Armed Forces, stakeholders in meeting India's security threats.
openaire +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
, 2020 Philosophiae Doctor - PhDHealth system in Sub-Saharan in Africa face multifaceted capacity challenges to fulfil their mandates of service provision and governance of their resources. Wide-ranging capacity development interventions exist to address these
Amde, Woldekidan Kifle
core +1 more source