The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Playing With Reality: Emergency Capacity Building Project simulations case study
, 2012 This Emergency Capacity Building (ECB) Project simulation case study focuses on the lessons learnt from implementing the ECB Project multi-agency simulations at the national level between April 2010 and March 2012, using the ECB Simulations ...
Lumsdon, Sarah, Hockaday, David
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Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
International R&D spillovers, absorptive capacity and relative backwardness: a panel smooth transition regression model [PDF]
We investigate how the country’s absorptive capacity and relative backwardness affect the impact of international R&D spillovers on domestic Total Factor Productivity (TFP).
Giuseppe Vittucci Marzetti +1 more
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Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Division of Epidemiology and Surveillance Capacity Development 2005 annual report
The Division of Epidemiology and Surveillance Capacity Development (DESCD) 2005 Annual Report is the division\u2019s first annual report, one that reflects the many changes that DESCD and the Centers for Disease Control and Prevention\u2019s (CDC) global
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Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Pulmonary Diffusing Capacity as a Factor of Aerobic Work Capacity
Taiikugaku kenkyu (Japan Journal of Physical Education, Health and Sport Sciences), 1972 Keiji Yamaji, Michio Ikai
openaire +2 more sources
Early Grade Literacy in Latin America and the Caribbean: Jamaica Stakeholder Mapping and Analysis
, 2019 The LAC Reads Capacity Program (LRCP) aims to increase the impact, scale, and sustainability of early grade literacy (EGL) activities in priority countries in Latin America and the Caribbean (Jamaica, Haiti, Dominican Republic, Guatemala, Honduras ...
USAID/LAC Reads Capacity Program
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