Results 131 to 140 of about 1,129,724 (343)

Fleet Size and Mix Vehicle Routing Problem (FSMVRP), Adapted Large Neighbourhood Search Heuristic Optimization ProposalWith a Plant-capacity and Multi-day Planning Algorithm: A Livestock Feed Industry Case Study

, 2023
Alperen Çelikdin
openalex   +1 more source

Optimized Power and Capacity Configuration Strategy of a Grid-Side Energy Storage System for Peak Regulation [PDF]

, 2023
Feng Guo, Jian Li, Chi Zhang, Yizhi Zhu, Caiyang Yu, Qingsong Wang, Giuseppe Buja   +6 more
openalex   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Multi‐operating characteristic analysis and loss optimization of novel large capacity high‐speed permanent magnet generator

IET Electric Power Applications
Recently, the development trend of large capacity generator has gradually shifted from electrical excitation generator to permanent magnet generator (PMG).
Bitian Ye, Ying Xie, Wei Cai, Huiyong Jin, Yutian Sun, Jing Bai   +5 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Optimization of Expressway Microgrid Construction Mode and Capacity Configuration Considering Carbon Trading [PDF]

, 2023
Lei Yao, Chongtao Bai, Hao Fu, Suhua Lou, Yan Fu   +4 more
openalex   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Mcaaco: a multi-objective strategy heuristic search algorithm for solving capacitated vehicle routing problems

Complex & Intelligent Systems
Vehicle routing is a critical issue in the logistics and distribution industry. In practical applications, optimizing vehicle capacity allocation can significantly improve route optimization performance and service coverage. However, solving this problem
Yanling Chen, Jingyi Wei, Tao Luo, Jie Zhou   +3 more
doaj   +1 more source

Capacity optimization of independent hybrid renewable energy system under different operational strategies based on improved gray wolf algorithm [PDF]

Jiaming Lu, Fei Lu Siaw, Tzer Hwai Gilbert Thio, J. J. Wang   +3 more
openalex   +1 more source