Results 91 to 100 of about 417,251 (308)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Research on reconfigurable topology layered equalization method based on maximum capacity utilization. [PDF]

PLoS One, 2023
Tu L, Xie M.
europepmc   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Strengthening capacity to apply health research evidence in policy making: experience from four countries [PDF]

, 2016
Increasing the use of evidence in policy making means strengthening capacity on both the supply and demand sides of evidence production. However, little experience of strengthening the capacity of policy makers in low- and middle- income countries has ...
K Aulakh, B, Whitworth, J, Jadeja, Nidhee, Barge, S, Hawkes, Sarah, Ghaffar, Abdul, Anwar, Iqbal, Jimenez, Michelle, Odubanjo, M Oladoyin, Jadeja, N, Ghaffar, A, Anwar, I, Jimenez, M, Hawkes, S, Shukla, A, Shukla, Abhay, Odubanjo, MO, K Aulakh, Bhupinder, Buse, K, Buse, Kent, Barge, Sandhya, Whitworth, Jimmy   +21 more
core   +1 more source

Fishing capacity analysis for open-access offshore fisheries: the case of Khanh Hoa’s offshore handline fishery in the South China Sea

Fisheries and Aquatic Sciences
This study analyzes the fishing capacity of the multi-species Khanh Hoa’s offshore handline fleet in the context of the World Trade Organization (WTO) agreement on subsidies for fisheries using a sample of 45 fishing vessels (15% of the total population).
Nguyen Dang Duc, Le Kim Long
doaj   +1 more source

Impact of enterprise digital transformation on capacity utilization: Evidence from China. [PDF]

PLoS One, 2023
Zhao N, Ren J.
europepmc   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

An important factor in job estimation: a nonlinear jobs-to-sales ratio with respect to capacity utilization

, 2012
[[abstract]]Many tools for economic impact evaluation, such as input-output models and computable general equilibrium models, rely on the jobs-to-sales ratio (JSR) to convert direct, indirect and induced effects of sales of final products into employment.
孫雅彥, Wong, Kam-Fai
core