Results 131 to 140 of about 1,308,034 (309)

DEBT, FINANCIAL FRAGILITY AND ECONOMIC GROWTH: A POST-KEYNESIAN MACROMODEL [PDF]

open access: yes
It is developed a mathematical post-keynesian macromodel of capacity utilization and growth in which the supply of credit-money is endogenous and firms' debt position - and thus the financial fragility of the economy - is explicitly modeled.
Antonio J. A. Meirelles   +1 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

A reexamination of the relationship between capacity utilization and inflation [PDF]

open access: yes
A review of the theoretical and empirical relationship between capacity utilization and inflation, employing a two-equation structural model that does not suffer from simultaneity bias and that appears to be stable over time.Industrial capacity ...
Paul W. Bauer
core  

Libra, a Multi-hop Radio Network Bandwidth Market [PDF]

open access: yes, 2007
Libra is a two-level market which assigns fractional shares of time to the transmitting nodes in local regions of a multi-hop network. In Libra, users are assigned budgets by management and users assign funding to services within their budget limits ...
Janson, Sverker, Rasmusson, Lars
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Industrial production and capacity utilization: the 2001 annual revision [PDF]

open access: yes
In late 2001, the Board of Governors of the Federal Reserve System published the annual revision of its index of industrial production and the related measures of capacity and capacity utilization for the period January 1992 to October 2001.
Carol Corrado   +2 more
core  

Opportunities and challenges with new railway planning approach in Sweden [PDF]

open access: yes, 2012
Long lead times in railway planning can give rise to a significant discrepancy between the original plan and the traffic eventually operated, resulting in inefficient utilization of capacity. Research shows that the railway sector in Sweden would benefit
Aronsson, Martin   +3 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Kanerva's sparse distributed memory with multiple hamming thresholds [PDF]

open access: yes
If the stored input patterns of Kanerva's Sparse Distributed Memory (SDM) are highly correlated, utilization of the storage capacity is very low compared to the case of uniformly distributed random input patterns.
Kaski, Kimmo, Pohja, Seppo
core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

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