Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Optimal Capacity Utilization and Reallocation in a German Bank Branch Network: Exploring Some Strategic Scenarios [PDF]
Quite a few studies have considered efficiency at the bank branch level by comparing mostly a single branch network, while an abundance of studies have focused on comparing banking institutions.
Bouye Ahmed Moulaye Hachem +3 more
core
Variation of Daily Care Demand in Swiss General Hospitals: Longitudinal Study on Capacity Utilization, Patient Turnover and Clinical Complexity Levels. [PDF]
J Med Internet Res, 2021 Sharma N +4 more
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
A Neo-Kaleckian Model of Profit Sharing, Capacity Utilization and Economic Growth [PDF]
This paper sets forth a Neo-Kaleckian model of capacity utilization and growth with distribution featuring a profit-sharing arrangement. While a given proportion of firms compensate workers with only a base wage, the remaining proportion do so with a ...
Gilberto Tadeu Lima
core
工程科学与技术, 2023 In the hydro-rich areas with high proportion of hydropower in the transmission network, the capacity utilization of transmission lines varies seasonally due to the impact of hydropower abundance and depletion characteristics.
Yang LIU +5 more
doaj
A Remote Capacity Utilization Estimator for WLANs
, 2014 III Abstract In WLANs, the capacity of a node is not fixed and can vary dramatically due to the shared nature of the medium under the IEEE 802.11 MAC mechanism. There are two main methods of capacity estimation in WLANs: Active methods based upon probing packets that consume the bandwidth of the channel and do not scale well. Passive methods based upon
openaire +2 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
RiceMelatonin (Mel), a multifunctional molecule, has emerged as a pivotal regulator of plant stress responses, enhancing antioxidant defenses, and modulating metabolic pathways.
Ihsan Muhammad +4 more
doaj +1 more source