Results 211 to 220 of about 11,867,276 (347)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Carbon Material and Electrolyte Composition Effects on the Performance of Prussian White Solid Boosters in Flow Batteries. [PDF]

ACS Omega
Abbasi V, Martínez-González E, Tirronen R, Kousar A, Rautama EL, Peljo P.   +5 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Hospital-Level NICU Capacity, Utilization, and 30-Day Outcomes in Texas.

JAMA Netw Open
Goodman DC, Stuchlik P, Ganduglia-Cazaban C, Tyson JE, Leyenaar J, Avritscher EBC, Rysavy M, Gautham KS, Lynch D, Stukel TA, Texas Neonatal Care Research Collaborative.   +10 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Trends in refinery capacity and utilization.

"DOE/RA-0010."Annual covers 2 areas: "Petroleum refineries in the United States" and "Foreign refinery exporting centers"; Dec. 1974- mid-year supplement covers U.S. only.Report year ends June 30.Mode of access: Internet.Vols.
United States. Department of Energy. Office of Oil and Natural Gas., United States. Department of the Interior. Office of Oil and Gas., United States. Federal Energy Office., United States. Department of Energy. Office of Oil and Natural Gas Supply Development., United States. Federal Energy Administration. Office of Oil and Gas.   +4 more
core  

Bismuth-guided cavity confinement breaks the stability-utilization trade-off in zinc powder anodes. [PDF]

Chem Sci
Jiang Y, Lan Z, Li C, Li X, Liu BT.
europepmc   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Spatial mismatches constrain high-value utilization of retired batteries for decarbonization in China. [PDF]

Environ Sci Ecotechnol
Xie H, Li H, Wang S, Han Z, Chen B, Lv H, Wang Y.   +6 more
europepmc   +1 more source

Behavior of Lithium Metal Anodes under Various Capacity Utilization and High Current Density in Lithium Metal Batteries

, 2017
Shuhong Jiao, Jian-Ming Zheng, Qiuyan Li, Xing Li, M. Engelhard, R. Cao, Ji-Guang Zhang, Wu Xu   +7 more
semanticscholar   +1 more source