Results 311 to 320 of about 1,102,528 (387)

Probing the Inhibitory Potential of Halogenated Symmetrical Formamidine Against MAO‐A and MAO‐B: Structural Elucidation, Molecular Dynamic Simulation and DFT Computational Studies

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT A halogenated symmetrical formamidine, N,N′‐bis(3‐chloro‐4‐fluorophenyl)formamidine (FCF) was synthesized by the condensation reaction between triethyl orthoformate and 3‐chloro‐4‐fluoroaniline in 1:2 ratio. The compound FCF was characterized by FT‐IR, mass, NMR (1H and 13C) spectroscopic techniques and the purity was confirmed by elemental ...
Segun D. Oladipo   +6 more
wiley   +1 more source

Rotenoids from the Roots of Vicia faba L. (Fabaceae): Structural Characterization, Cytotoxic Effects, and Molecular Docking

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The chemical study of the ethanolic extract from the roots of Vicia faba led to the isolation of two isoflavonoids, alfalone and 8‐O‐methylretusine, as well as a mixture of rotenoids, including clitoriacetal and clitoriacetal B, the latter of which is reported for the first time.
Victor Menezes Sipoloni   +8 more
wiley   +1 more source

Chromenone derivatives as CRM1 Inhibitors for Targeting Glioblastoma

open access: yesChemBioChem, Accepted Article.
Glioblastoma (GBM) is one of the most aggressive and deadly cancers. Due to the complexity and redundancy within signaling networks in GBM, targeted inhibitors of specific pathways have shown only limited success. The nuclear export receptor Chromosome Region Maintenance 1 (CRM1) has recently emerged as a promising therapeutic target, as its inhibition
Wolfgang Link   +10 more
wiley   +1 more source

Incidence, Disease Spectrum, and Outcomes of Tuberculous Meningitis in South African Children: The Initial Impact of COVID-19. [PDF]

open access: yesTrop Med Infect Dis
Namukuta VE   +11 more
europepmc   +1 more source

A Six‐Step Approach for Optimizing Ultrasound‐Guided Femoral Artery Access

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Femoral arterial access is fundamental to interventional cardiology, especially for complex procedures that require large‐bore devices. However, vascular complications arising from suboptimal puncture techniques highlight the need for meticulous practice.
Fernando Luiz de Melo Bernardi   +6 more
wiley   +1 more source

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