Results 61 to 70 of about 553,818 (311)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Alimentos e Nutrição, 2011 O presente trabalho teve como objetivo elaborar três bebidas mistas à base de cajá e manga, na forma “pronto para beber”, com propriedades prebióticas e avaliar as suas características químicas, físico-químicas e sensoriais.
Larissa Morais Ribeiro da SILVA +5 more
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Increasing beef production won’t reduce emissions [PDF]
, 2017 BP is supported by a grant from CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior) through the Brazilian Science without Borders programme (number 88881.068115/2014-01).
Carranza +13 more
core +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
On the equivalence between logic programming semantics and argumentation semantics [PDF]
, 2014 This work has been supported by the National Research Fund, Luxembourg (LAAMI project), by the Engineering and Physical Sciences Research Council (EPSRC, UK), grant Ref. EP/J012084/1 (SAsSy project), by CNPq (Universal 2012 – Proc. 473110/2012-1), and by
Alcântara, João +3 more
core +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Prismas, 2018 Dossier: Libros, editoriales y ciencias sociales Prismas Nº22 (2018)
Lidiane Soares Rodrigues +1 more
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Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
EspacesTemps.net, 2002 Pour commencer... Un préalable ! ! ! ! : Lire les trois ou quatre derniers rapports du jury à propos de l’épreuve sur dossier (parus dans la revue Historiens et Géographes ). Philippe Poirrier , Aborder l’histoire , Mémo-Seuil, 2000. En 96 pages ( !) une
Christian Delacroix +2 more
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