Results 41 to 50 of about 37,962 (287)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Controlling the Organization of Colloidal Sphero-Cylinders Using Confinement in a Minority Phase
Gels, 2018 We demonstrate experimentally that a phase-separating host solvent can be used to organize colloidal rods into different cluster and network states. The rods are silica sphero-cylinders which are preferentially wet by the water-rich phase of an oil–water
Niek Hijnen, Paul S. Clegg
doaj +1 more source
Experimental study on the rise of aqueous foams in vertical pipes
Frontiers in Physics, 2022 In this paper we report experiments on the growth of dry foams and their rise in vertical pipes of different circular cross-sectional radii with length over diameter ratios in the interval 25 ≤ h/D ≤ 80 for applications in the study of fracture ...
Valeriano S. Álvarez Salazar +4 more
doaj +1 more source
, 2011 Capillarity approximation is used to study the free-energy landscape of nucleation when an intermediate metastable phase exists. The critical nucleus that corresponds to the saddle point of the free-energy landscape as well as the whole free-energy ...
Johnson W. A. +3 more
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
SensorsPoint-of-care (PoC) devices offer a promising solution for fast, portable, and easy-to-use diagnostics. These characteristics are particularly relevant in agrifood fields like viticulture where the early detection of plant stresses is crucial to crop ...
Cristiana Domingues +5 more
doaj +1 more source
Experiment—Simulation Comparison in Liquid Filling Process Driven by Capillarity
Micromachines, 2022 This paper studies modifications made to the Bosanquet equation in order to fit the experimental observations of the liquid filling process in circular tubes that occurs by capillary force.
Wei Hua +4 more
doaj +1 more source
Phreatic seepage flow through an earth dam with an impeding strip [PDF]
, 2020 New mathematical models are developed and corresponding boundary value problems are analytically and numerically solved for Darcian flows in earth (rock)–filled dams, which have a vertical impermeable barrier on the downstream slope.
Kacimov, AR, Simunek, J, Yakimov, ND
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Biomimetics, 2023 In surgical dentistry, suture material is the only foreign body that remains in the tissues after surgery, and it can lead to several negative reactions, for example, infection of the wound.
Alexey A. Pcheliakov +11 more
doaj +1 more source