Results 181 to 190 of about 4,144,329 (348)

Bioprinting Perfusable and Vascularized Skeletal Muscle Flaps for the Treatment of Volumetric Muscle Loss

Advanced Healthcare Materials, EarlyView.
Volumetric muscle loss (VML) due to trauma or surgery, often leads to physical impairments. Traditional treatments rely on autologous flaps, limited by muscle availability often leading to donor site morbidity. This study presents multimodal bioprinting as an innovative approach for fabricating vascularized muscle flaps with 3D‐printed macrovessels ...
Eliana O. Fischer, Anna Tsukerman, Majd Machour, Margarita Shuhmaher, Asaf Silverstein, Maya Yaakov, Orit Bar‐Am, Lior Debbi, Shulamit Levenberg   +8 more
wiley   +1 more source

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

Advanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang, Zenan Huang, Zhenzhong Han, Jing Luan, Zihan Li, Xutong Guo, Dongxu Yang, Yazhou Cui, Jinxiang Han, Duo Xu   +9 more
wiley   +1 more source

Theoretical model and experimental verification of seepage-transition-spontaneous imbibition in water migration of water-injected coal. [PDF]

Sci Rep
Sun Q, Guo Y, Chen J, Yang X, Yan X, Hu X, Guo L, Jin YC.   +7 more
europepmc   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

The effect of modified polymer on the change rule of physical properties of different gradation coal gangue. [PDF]

Sci Rep
Sun Z, Wang X, Yang J, Shi C, Zhao T, Li R, Li C, Deng M, Yang C.   +8 more
europepmc   +1 more source

Organoid‐Like Neurovascular Spheroids Promote the Recovery of Hypoxic‐Ischemic Skin Flaps Through the Activation of Autophagy

Advanced Healthcare Materials, EarlyView.
Highly sprouting organoid‐like neurovascular spheroids (NVUs) are developed, featuring cell‐loaded poly‐3‐hydroxybutyrate 4‐hydroxybutyrate(P34HB) porous microsphere cores embedded within Gelatin Methacryloyl. NVUs formed complex vascular plexuses and secreted extracellular matrix in vitro, simulating autologous nerves and blood interaction.
Junjin Jie, Jingyi Ju, Zhenxing Wang, Jun Chen, Lin‐Ping Wu, Jiaming Sun   +5 more
wiley   +1 more source

Insulin transport across capillaries is rate limiting for insulin action in dogs. [PDF]

, 1989
Yan Yang, I D Hope, Marilyn Ader, Richard N. Bergman   +3 more
openalex   +1 more source

Development of Itaconate Polymers Microparticles for Intracellular Regulation of Pro‐Inflammatory Macrophage Activation

Advanced Healthcare Materials, EarlyView.
This study develops itaconate‐based polymer microparticles (IA‐MPs) for macrophage‐targeted intracellular delivery, overcoming the limitations of traditional itaconate administration. IA‐MPs achieve controlled release through phagocytosis, reducing pro‐inflammatory cytokine expression and reprogramming macrophage metabolism toward glycolysis.
Kaitlyn E. Woodworth, Zachary S.C.S. Froom, Natasha D. Osborne, Christian N. Rempe, Brenden Wheeler, Kyle Medd, Neal I. Callaghan, Huikang Qian, Abhinav P. Acharya, Carlie Charron, Locke Davenport Huyer   +10 more
wiley   +1 more source

Scalable Multistep Roll-to-Roll Printing of Multifunctional and Robust Reentrant Microcavity Surfaces via a Wetting-Induced Process. [PDF]

Adv Mater
Choi SH, Shin S, Kim WY, Lee JM, Park SR, Kim H, Woo K, Kwon S, Fang NX, Kim S, Cho YT.   +10 more
europepmc   +1 more source

Biofunctionalization of ADA‐GEL Hydrogels Based on the Degree of Cross‐Linking and Polymer Concentration Improves Angiogenesis

Advanced Healthcare Materials, EarlyView.
The biocompatibility of alginate dialdehyde (ADA) and gelatin (GEL) hydrogels cross‐linked with human transglutaminase (hTG) is demonstrated in vivo with a high degree of stability and angiogenic potential. The additional enzymatic cross‐linker hTG and the increased concentration improve stability and angiogenic potential. The X‐ray microscopy (XRM) is
Stefanie Heltmann‐Meyer, Rainer Detsch, Jonas Hazur, Lasse Kling, Sabrina Pechmann, Rajkumar Reddy Kolan, Justus Osterloh, Aldo R. Boccaccini, Silke Christiansen, Carol I. Geppert, Andreas Arkudas, Raymund E. Horch, Dominik Steiner   +12 more
wiley   +1 more source