Results 61 to 70 of about 375,258 (338)
Surface morphological evolutions on single crystal films by strong anisotropic drift-diffusion under the capillary and electromigration forces [PDF]
, 2006 The morphological evolution of voids at the unpassivated surfaces and the sidewalls of the single crystal metallic films are investigated via computer simulations by using the novel mathematical model developed by Ogurtani relying on the fundamental ...
Aytac Celik +3 more
core +2 more sources
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Molecular Oncology, EarlyView.Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides +13 more
wiley +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Frontiers in Aging Neuroscience, 2021 Prostaglandin E2 (PGE2) has been widely proposed to mediate neurovascular coupling by dilating brain parenchymal arterioles through activation of prostanoid EP4 receptors.
Amanda C. Rosehart +7 more
doaj +1 more source
Wetting of anisotropic sinusoidal surfaces - experimental and numerical study of directional spreading [PDF]
, 2014 Directional wettability, i.e. variation of wetting properties depending on the surface orientation, can be achieved by anisotropic surface texturing. A new high precision process can produce homogeneous sinusoidal surfaces (in particular parallel grooves)
Anselme, K. +5 more
core +2 more sources
Molecular Oncology, EarlyView.Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
Effects of Tube Radius and Surface Tension on Capillary Rise Dynamics of Water/Butanol Mixtures
Applied Sciences, 2021 Capillary-driven action is an important phenomenon which aids the development of high-performance heat transfer devices, such as microscale heat pipes.
Seungyeop Baek +7 more
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Silicon ribbon growth by a capillary action shaping technique [PDF]
Substantial improvements in ribbon surface quality are achieved with a higher melt meniscus than that attainable with the film-fed (EFG) growth technique.
Ciszek, T. F. +3 more
core +5 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source