Results 191 to 200 of about 228,053 (289)

Urinary Collagen Peptides Predict Mortality

PROTEOMICS, EarlyView.
ABSTRACT Organ fibrosis caused by the presence of excessive extracellular matrix (ECM) is related to mortality. Urinary peptide signatures were reported to be predictive of death in SARS‐CoV‐2 and chronic kidney disease. Such signatures were composed for 68% of collagen fragments.
Maria Frantzi, Felix Keller, Agnieszka Latosinska, Joachim Beige, Alexandre Mebazaa, Anaïs Caillard, Dewei An, Paul Perco, Joost P. Schanstra, Lorenzo Catanese, Ralph Wendt, Harald Rupprecht, Jan A. Staessen, Antonia Vlahou, Harald Mischak, Justyna Siwy   +15 more
wiley   +1 more source

Enhanced accuracy and sensitivity in detecting FMR1 CGG repeats: a multicenter evaluation of a novel PCR-capillary electrophoresis assay. [PDF]

World J Pediatr
Shou XY, Zhu ZW, Jin H, Hu JH, Yan TZ, Zhong QY, Li WH, Mao JH, Dong MY, Xu Q, Ni SQ.   +10 more
europepmc   +1 more source

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

Journal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá, Ladislav Androvič, Marcela Filipová, Michal Pechar, Richard Laga   +4 more
wiley   +1 more source

High dynamic range capillary electrophoresis method for sensitive detection of low-frequency driver mutations. [PDF]

Sci Rep
Tamamura N, Hagiwara Y, Kato H, Ono Y, Takahashi K, Koyama K, Sato H, Okada T, Kawabata H, Ohtaki Y, Maeda C, Mori M, Chiba SI, Tanino M, Taniue K, Anazawa T, Inaba R, Mizukami Y.   +17 more
europepmc   +1 more source

The Mycobacterium tuberculosis Rv0132c Gene Product Mtb‐FGD2 Can Act as an F420‐Dependent Glucose Dehydrogenase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The role of the cell envelope‐associated Rv0132c/FGD2 from Mycobacterium tuberculosis has long been a subject of debate. Importantly, FGD2 is found only in pathogenic mycobacteria, making it a potential drug target. While some suggest it functions as a glucose‐6‐phosphate dehydrogenase, others propose it acts instead as an F420‐dependent ...
Adewale V. Aderemi, Matthew Snee, Richard B. Tunnicliffe, Linus O. Johanissen, Matthew J. Cliff, Colin W. Levy, Derren J. Heyes, Marina Golovanova, Thomas A. Jowitt, Sam Hay, Andrew W. Munro, Jonathan P. Waltho, David Leys   +12 more
wiley   +1 more source

A Spectroscopy Solution for Contactless Conductivity Detection in Capillary Electrophoresis. [PDF]

Micromachines (Basel)
Drevinskas T, Maruška A, Ihara H, Takafuji M, Jonušauskas L, Armonavičius D, Stankevičius M, Bimbiraitė-Survilienė K, Skrzydlewska E, Ragažinskienė O, Kuwahara Y, Nagaoka S, Kaškonienė V, Kubilienė L.   +13 more
europepmc   +1 more source

Synthetic polymer nanocarrier enhances dsRNA stability but not RNAi efficacy in Brassicogethes aeneus

Pest Management Science, EarlyView.
Experimental setup for dsRNA feeding in Brassicogethes aeneus to evaluate the effect of a synthetic polymer nanocarrier on RNAi efficiency. The experiment assessed whether the nanocarrier enhances RNAi after oral dsRNA delivery. (a) Stability of dsRNA–nanocarrier complexes was tested in simulated gut conditions. (b) Gene expression of αCOP and dre4 was
Triin Kallavus, Liina Soonvald, Iris Callewaert, Ana Isabel Silva, Ericmar Ávila Dos Santos, Silva Vilumets, Riina Kaasik, Sven Vereecken, Lenny Van Daele, Peter Dubruel, Jonathan Willow, Clauvis Nji Tizi Taning, Kristof De Schutter, Eve Veromann   +13 more
wiley   +1 more source

Contactless Conductivity Detection for Capillary Electrophoresis-Developments From 2020 to 2024. [PDF]

Electrophoresis
Hauser PC, Kubáň P.
europepmc   +1 more source

The scale matters: A review on stimuli‐responsive microrobots categorized by scale for biomedical applications

Responsive Materials, EarlyView.
We systematically summarize how each scale dictates fundamental choices in design feature, manufacturing technology, driving mechanism, and control strategy, which are inherently governed by scale‐dominated physical principles. Furthermore, the application of scale‐determined operation modes of microrobots across different stages of medical ...
Hang Yin, Yujing Li, Guanghao Wu, Yubing Guo   +3 more
wiley   +1 more source

Development of a Low-Cost and Easy-Assembly Capillary Electrophoresis System for Separation of DNA. [PDF]

Bioengineering (Basel)
Li J, Fan S, Zhu J, Yang B, Li Z, Zhang D, Yamaguchi Y.   +6 more
europepmc   +1 more source