Results 61 to 70 of about 125,910 (310)

Capillary Electrophoresis Mass Spectrometry-Based Metabolomics of Plasma Samples from Healthy Subjects in a Cross-Sectional Japanese Population Study

Metabolites, 2021
For large-scale metabolomics, such as in cohort studies, normalization protocols using quality control (QC) samples have been established when using data from gas chromatography and liquid chromatography coupled to mass spectrometry.
Hiroyuki Yamamoto, Makoto Suzuki, Rira Matsuta, Kazunori Sasaki, Moon-Il Kang, Kenjiro Kami, Yota Tatara, Ken Itoh, Shigeyuki Nakaji   +8 more
doaj   +1 more source

Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy

Advanced Materials, EarlyView.
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla, Jacqueline J. Li, Qunzhou Zhang, Korey Patwari, Shihong Shi, Hannah M. Yamagata, Ryann A. Joseph, Briyanna N. Hymms, Sridatta V. Teerdhala, Emily Fitzgerald, Ori Z. Chalom, Kushol Gupta, Mohamad‐Gabriel Alameh, Drew Weissman, Anh D. Le, Michael J. Mitchell   +15 more
wiley   +1 more source

Application of Capillary Electrophoresis to Analysis of Aconitine Alkaloids [PDF]

, 2004
Capillary electrophoresis was applied to the analysis of aconitine alkaloids. An AccuSepcapillary column (75 μm i.d. × 60cm), 0.4M di-sodium hydrogenphosphate - 0.2M citric acid buffer (pH7.0) as the electrophoretic buffer, and 3.5kV as the ...
庵原, 聡美, 秋保, 由美子, Akiho, Yumiko, イハラ, サトミ, Yoshizaki, Fumihiko, Sasaki, Keiko, 下田, はる美, シモダ, ハルミ, ササキ, ケイコ, アキホ, ユミコ, Shimoda, Harumi, Ihara, Satomi, 吉崎, 文彦, 佐々木, 桂子, ヨシザキ, フミヒコ   +14 more
core  

An investigation into the sample preparation procedure and analysis of cyanoacrylate adhesives using capillary electrophoresis [PDF]

, 2007
In this study, the trace acid profile of cyanoacrylate adhesives was studied using capillary electrophoresis. Liquid–liquid extraction was employed as the sample preparation step before separation by capillary electrophoresis.
Kincaid, Brendan J., Smyth, Malcolm R., van Hoof, Nicole, Regan, Fiona, Whitaker, Gillian, Leonard, Raymond G.   +5 more
core   +1 more source

Detection of Mutations in Exon 8 of TP53 by Temperature Gradient 96-Capillary Array Electrophoresis

BioTechniques, 2002
Various capillary electrophoresis applications have increasingly been utilized in mutation detection. Separation of two species is either based on secondary structure or differences in melting of DNA due to the mutation.
A. Torgunrud Kristensen, J. Bjørheim, M. Minarik, K.-E. Giercksky, P.O. Ekstrøm   +4 more
doaj   +1 more source

Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution‐Based Biophysical Analyses

Advanced Materials, EarlyView.
AF4‐UV‐DLS‐MALS‐SAXS resolves previously inaccessible targeted lipid nanoparticle (tLNP) subpopulations that differ in size, shape, and composition. Correlation of subpopulation‐resolved biophysical properties with in vivo RNA delivery reveals that targeted placental transfection is associated with distinct tLNP subpopulations rather than ensemble ...
Hannah C. Geisler, Hannah C. Safford, Ajay S. Thatte, Marshall S. Padilla, Elisa Battistini, Hannah M. Yamagata, Violet M. Ullman, Alex Chan, Benjamin E. Nachod, Anushka Agrawal, Maxwell B. Watkins, Jesse B. Hopkins, Andrew Tsourkas, Kushol Gupta, Michael J. Mitchell   +14 more
wiley   +1 more source

Hybrid Amyloid–Boron Nitride Aerogels for Lightweight Sound Insulation

Advanced Materials, EarlyView.
Amyloid fibrils template the mild formation of boron nitride–rich hybrid aerogels with hierarchical porosity, enhanced BN‐like ordering, and fibril‐reinforced mechanics. These ultralight materials combine thermal stability with strong sound absorption and transmission loss, offering a sustainable bio‐assisted route toward lightweight acoustic shields ...
Mohammad Peydayesh, Andrin Lustgarten, Stefan Schoenwald, Enrico Boschi, My Hanh Bui, Ali Miserez, Felix Donat, Christoph R. Müller, Raffaele Mezzenga   +8 more
wiley   +1 more source

Capillary electrophoresis immunoassay using magnetic beads [PDF]

, 2008
Protein A-coated magnetic beads (0.3 μm) have been trapped in a small portion of a neutrally coated capillary (50 μm id). Anti-β-lactoglobulin (β-LG) antibodies have then been immobilized on the beads through strong affinity with protein A to ...
Busnel, Jean-Marc, Zhang, Xin-Xiang, Chen, Hong-Xu, Gassner, Anne-Laure, Peltre, Gabriel, Girault, Hubert H.   +5 more
core   +1 more source

Navigating Lipid Nanostructure Design Space Through Continuous Microfluidic Automation

Advanced Materials, EarlyView.
LipidXplorer is a novel microfluidic platform which enables rapid navigation of lipid particle design space for high‐resolution phase mapping, lipid nanoparticle optimization, membrane biophysics, and functional nanomaterial discovery. It combines programmable composition control, continuous nanoparticle formation, and automated well‐plate collection ...
Bradley Diggines, Marcus Fletcher, Manuel Bibrowski, Karnyart Samnuan, Rongjun Chen, David J. Peeler, Amjad Abouselo, Morag R. Hunter, Molly M. Stevens, Nicholas J. Brooks, Yuval Elani   +10 more
wiley   +1 more source

Photoactive Tweezers

Advanced Materials, EarlyView.
A photoactive tweezers system based on photoactive colloids is developed and systematically investigated in this study. Through experimental and theoretical methods, we demonstrate that the photoredox reaction catalyzed by a dye‐sensitized TiO2 particle generates a strong positive phototaxis, enabling self‐entrapment in the beam center.
Jingyuan Chen, Qingxin Guo, Shiwei Zhang, Donghao Cui, Changjin Wu, Pei Xu, Wei Wang, Kai Lou, Binglin Zeng, Jinyao Tang   +9 more
wiley   +1 more source