ABSTRACT This study aimed to explore the differences of peripheral blood (PB) and bone marrow serum lipidomic profiles in severe aplastic anemia (SAA) patients and their significance in predicting earlier immunosuppressive therapy (IST) response. A cohort of 11 newly diagnosed SAA patients and 15 healthy controls were enrolled between June 2020 and ...
Zexing Sun +11 more
wiley +1 more source
Use of glycerol triheptanoate as a marker for processed animal by-products - results from 2010-2024. [PDF]
Grelik A, Kowalczyk E, Kwiatek K.
europepmc +1 more source
Dietary supplementation with stearidonic acid–rich Echium and Ahiflower oils increases EPA levels across multiple mouse tissues, while DHA responses remain tissue‐specific and limited, supporting the strategic use of plant‐based omega‐3 sources for EPA‐focused interventions. ABSTRACT Omega‐3 fatty acids (n‐3 FA), particularly eicosapentaenoic acid (EPA)
Letícia V. Segre +2 more
wiley +1 more source
ABSTRACT Increasing evidence suggests that dairy consumption may decrease the risk of chronic diseases. However, this association remains unclear due to methodological limitations. As a part of a secondary analysis, we used compound‐specific stable isotope analysis to increase the accuracy of the dairy FA biomarkers (15:0, 17:0), considering that each ...
Camilla Parzanini +8 more
wiley +1 more source
Metabolomics and Pharmacometabolomics: Advancing Precision Medicine in Drug Discovery and Development. [PDF]
Stolaki EV, Psatha K, Aivaliotis M.
europepmc +1 more source
Linear polyglycerol is proposed as a PEG‐alternative in mRNA‐loaded lipid nanoparticles to limit activation of anti‐PEG antibodies and reduce immunogenicity. Resulting nanoparticles may provide similar gene delivery capabilities, while preventing binding of anti‐PEG antibodies compared to PEGylated counterparts.
Yara Ensminger +8 more
wiley +1 more source
Development of a homogeneous liquid-liquid microextraction method using lighter than water solvents for the extraction of some pesticides from distillate samples followed by GC-FID determination. [PDF]
Ghoreishizadeh M +3 more
europepmc +1 more source
Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley +1 more source
Phytochemical Profiling and Antioxidant Activity of <i>Justicia thunbergioides</i> (Lindau) Leonard (Acanthaceae): A Promising Source of Therapeutic Metabolites. [PDF]
Provensi LR +6 more
europepmc +1 more source
Do capillary dried blood spot concentrations of gamma-hydroxybutyric acid mirror those in venous blood? : a comparative study [PDF]
Abanades +19 more
core +1 more source

