Results 81 to 90 of about 98,360 (263)

Endothelial Damage in Sepsis: The Interplay of Coagulopathy, Capillary Leak, and Vasoplegia—A Physiopathological Study

open access: yesClinics and Practice
Background: Sepsis remains a leading cause of mortality worldwide, and understanding endothelial damage is crucial for improving patient outcomes. Endothelial dysfunction in sepsis contributes to coagulopathy, increased capillary permeability, and ...
Gianni Turcato   +9 more
doaj   +1 more source

Stage‐Adaptive Janus Microneedle System for Redox‐Immune Regulation and Mitochondrial Protection in Infected Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin   +13 more
wiley   +1 more source

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

open access: yesAdvanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

Stress sensitivity analysis of vuggy porous media based on two-scale fractal theory

open access: yesScientific Reports
Interparticle pore space and vugs are two different scales of pore space in vuggy porous media. Vuggy porous media widely exists in carbonate reservoirs, and the permeability of this porous media plays an important role in many engineering fields. It has
Zhaoqin Huang   +4 more
doaj   +1 more source

Mixing‐Driven Defects and Composition Evolution in Multi‐Material Metal Additive Manufacturing

open access: yesAdvanced Science, EarlyView.
Operando synchrotron X‐ray imaging coupled with high‐fidelity multiphysics modeling uncovers how inter‐material mixing reshapes keyhole dynamics and drives distinct pore‐formation pathways in multi‐material laser powder bed fusion (LPBF). Composition‐dependent instabilities trigger defects, whereas rescanning suppresses porosity and homogenizes Cu ...
Zhilang Zhang   +5 more
wiley   +1 more source

Study on the Influence of Sustained Axial Compression and Tension on the Permeability Properties of Panel Concrete

open access: yesBuildings
The anti-seepage performance of concrete directly affects the anti-seepage effect and durability of the concrete face slab of the rockfill dam. Since the panel concrete is often in a complex stress state in practical engineering, its permeability ...
Xin Zhang   +5 more
doaj   +1 more source

Unidirectional Evaporation‐Induced Tunable and Continuous Gradient Composite Structure for Absorption‐Dominant Electromagnetic Interference Shielding

open access: yesAdvanced Science, EarlyView.
A continuous conductivity gradient is formed in a porous MXene/melamine foam via directional evaporation, thereby improving impedance matching and enhancing electromagnetic attenuation. The resulting monolithic composite delivers absorption‐dominant EMI shielding with ultralow reflection, offering a simple route toward lightweight EMI shielding ...
Dawei Zhang   +6 more
wiley   +1 more source

Architecture‐Controlled Hierarchical Carbon‐Based Current Collector for Mitigating Interfacial Instabilities in Lithium‐Metal Anodes

open access: yesAdvanced Science, EarlyView.
A defect‐engineered, hierarchically porous carbon black/CNT current collector guides lithiophilic nucleation in 3D architecture. Steam‐created defects enable uniform Li plating, while CNTs provide conductivity and a lightweight framework, suppressing dendrites and side reactions for stable anode‐free cells.
Seo Hui Kang   +3 more
wiley   +1 more source

High Free‐Volume Imidazole‐Based Ionomers for High‐Temperature Proton Exchange Membrane Fuel Cells

open access: yesAdvanced Science, EarlyView.
High free‐volume imidazole‐based ionomers (PF4IM‐72) enable enhanced phosphoric acid uptake and efficient proton transport, delivering peak power densities of 0.645 W cm−2 at 160 °C and 0.838 W cm−2 at 200 °C in HT‐PEMFCs. This work highlights a promising platform for next‐generation ionomers with improved high‐temperature performance and stability ...
Ge Chao   +7 more
wiley   +1 more source

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

open access: yesAdvanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv   +13 more
wiley   +1 more source

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