Results 101 to 110 of about 21,885 (283)

Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas

open access: yesAdvanced Science, EarlyView.
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen   +9 more
wiley   +1 more source

SETDB2 Mitigates Podocyte Dysfunction in Diabetic Kidney Disease Through Epigenetic Silencing of SMAD3

open access: yesAdvanced Science, EarlyView.
SETDB2 epigenetically represses Smad3 transcription by increasing H3K9me3 enrichment at its promoter, thereby mitigating podocyte dysfunction in DKD. The transcription factor TCF21 binds directly to the Setdb2 promoter and enhances its expression in podocytes. Abstract Podocyte dysfunction represents both an early pathological hallmark and a key driver
Lanfang Li   +14 more
wiley   +1 more source

Magnetic Resonance Imaging Reveals Meningeal Lymphatic Impairment in Lung Adenocarcinoma Brain Metastasis Progression

open access: yesAdvanced Science, EarlyView.
This study demonstrates meningeal lymphatic impairment associated with lung adenocarcinoma brain metastasis progression in both human patients and mouse models, establishes clinically applicable non‐invasive imaging biomarkers for quantitative analyzing mLV structure and function, and reveals mLVs as robust prognostic indicators and promising potential
Yuan Zhang   +15 more
wiley   +1 more source

Polarization‐Multiplexed Metalens Enables Switchable and Compact Chromatic Confocal Sensing with Dual‐Mode Precision Control

open access: yesAdvanced Science, EarlyView.
This work breaks conventional design paradigms by leveraging a polarization‐multiplexed metasurface to create the first chromatic confocal sensor with dynamically switchable measurement performance, achieving 10‐fold miniaturization (Ø1 mm vs cm‐scale conventional probes).
Zhicheng Zhao   +5 more
wiley   +1 more source

The Modular Architecture of Capital

open access: yes, 2023
S. A. Hamed Hosseini, Barry K. Gills
openaire   +1 more source

Capital flows during the pandemic: lessons for a more resilient international financial architecture

open access: green, 2020
Fernando Eguren Martin   +6 more
openalex   +1 more source

Compact Optical Reservoir Computing via Luminescence Dynamics in Rare‐Earth Ions‐Doped Nanocrystals

open access: yesAdvanced Science, EarlyView.
A functionally compact optical reservoir computing platform is demonstrated using rare‐earth ion‐doped nanocrystals, whose intrinsic nonlinear luminescence dynamics and multi‐timescale metastable states provide nonlinear mapping and fading memory without bulky delays or resonant structures.
Junyan Chen   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy